Agomelatine

Uses of Agomelatine

Aesculin+cinchocaine+framycetin+hydrocortisone used for hemorrhoids/piles. It helps relieve pain, irritation, discharge and itchiness.

How Agomelatine Works

Agomelatine is a psychoanaleptics. It is an antidepressant that works by binding to melatonergic agonists to re-synchronize disrupted circadian rhythms, which occur in depressed individuals. It also works as an antagonist to increase the release of noradrenaline and dopamine which is known to be low in people with depression.

Side Effects of Agomelatine

Rash, Discomfort At Area Of Application

Information About Agomelatine

Agomelatine is a melatonergic antidepressant used to treat major depressive disorder in adults in Singapore. Available as a 25mg–50mg oral tablet taken once daily at bedtime, it is HSA-registered and available on prescription only in Singapore. Unlike conventional antidepressants, it restores disrupted circadian rhythms by activating melatonin MT1 and MT2 receptors while blocking serotonin 5-HT2C receptors, improving both mood and sleep quality without causing sexual dysfunction or weight gain. A valid doctor's consultation is required before dispensing. Order Agomelatine online at DoctorOnCall Singapore with same-day delivery available. Speak to a DoctorOnCall physician today to check if Agomelatine is right for you.


Agomelatine is a medication commonly used to treat major depressive disorder by helping regulate mood and restore healthy sleep patterns. It works by acting on melatonin receptors and blocking certain serotonin receptors in the brain, which may improve mood and circadian rhythm balance. Agomelatine belongs to a class of medications known as antidepressants and is widely used in the management of depression and related sleep disturbances. Find affordable Agomelatine options from trusted brands at DoctorOnCall.

Conclusion

Consult our doctors online for safe and effective use of Agomelatine tailored to your health needs. Find the best prices for affordable Agomelatine tablets at DoctorOnCall Singapore.


Warnings

Kidney Use With Care

Agomelatine use in patients with renal impairment has shown no dose adjustment needed. However, further data on this is very limited. Therefore, it is advised to be cautious when prescribing this drug.

Alcohol Not Advisable

It is unsafe to consume alcohol with Agomelatine. Taking Agomelatine with alcohol may have affect the liver function.

Pregnancy Not Safe

There are limited data available on the effect of Agomelatine on human pregnancy. Therefore, it is considered safe to avoid the use of this medication altogether during pregnancy.

Driving Generally Safe

Agomelatine is for external application. Therefore, it does not interfere with the ability to drive.

Liver High Risk

Agomelatine is contraindicated in patients with liver impairment.

Lactation Limited Data

Available data indicate the excretion of Agomelatine in the mother's milk. However, data available does not explain the risk implicated by the presence of Agomelatine in milk upon the infant consuming it.

Frequently Asked Questions

Written by

Dr. Adeline Carol Peters

, Bachelor of Medicine and Bachelor of Surgery (MBBS) — Manipal Academy of Higher Education (MAHE)

Reviewed by

Dr. Mohd Izzat Amir Bin Awang

, Doctor of Medicine (MD), University of Mansoura - Manchester