Amiloride + Hydrochlorothiazide

Uses of Amiloride + Hydrochlorothiazide

The combination of Amiloride and Hydrochlorothiazide belongs to the class of diuretics and is indicated for the treatment of hypertension and edema associated with congestive heart failure, cirrhosis of the liver, and nephrotic syndrome.

How Amiloride + Hydrochlorothiazide Works

Amiloride inhibits sodium reabsorption in the distal tubules of the kidneys, reducing potassium excretion. Hydrochlorothiazide enhances diuresis by inhibiting sodium reabsorption, leading to increased water and sodium excretion, albeit with potassium loss. Together, they create a synergistic effect for managing hypertension and edema.

Side Effects of Amiloride + Hydrochlorothiazide

Dizziness, Headache, Nausea, Vomiting, and Increased Blood Potassium Levels.

Information About Amiloride + Hydrochlorothiazide

Amiloride + Hydrochlorothiazide is a combination potassium-sparing and thiazide diuretic used to treat hypertension and oedema while minimising diuretic-induced potassium loss in Singapore. Available as a fixed-dose oral tablet (5mg/50mg) taken once daily with food, it is HSA-registered and available on prescription only in Singapore. The amiloride component counteracts the potassium-wasting effect of hydrochlorothiazide, allowing effective diuresis and blood pressure reduction without the need for separate potassium supplementation in most patients. A valid doctor's consultation is required before dispensing. Order Amiloride + Hydrochlorothiazide online at DoctorOnCall Singapore with same-day delivery available. Speak to a DoctorOnCall physician today to check if Amiloride + Hydrochlorothiazide is right for you.

Amiloride + Hydrochlorothiazide is a combination medication commonly used to treat high blood pressure and fluid retention by helping the body remove excess salt and water while maintaining balanced potassium levels. Hydrochlorothiazide increases urine production to reduce fluid buildup, while Amiloride helps prevent excessive potassium loss caused by diuretics. This medication belongs to a class of drugs known as diuretics and is widely used in the management of hypertension and oedema. Find affordable Amiloride + Hydrochlorothiazide options from trusted brands at DoctorOnCall.

Conclusion

Consult our doctors online for safe and effective use of Amiloride + Hydrochlorothiazide tailored to your health needs. Find the best prices for affordable Amiloride + Hydrochlorothiazide tablets at DoctorOnCall Singapore.

Warnings

Kidney Use With Care

Amiloride + Hydrochlorothiazide has potential side effect on the kidney as it has medium diuretic effect. However, this drug should be used with caution if combined with other diuretics as it may cause hyperkalemia. Amiloride + Hydrochlorothiazide is contraindicated in renal failure.

Alcohol Not Advisable

It is not advisable to take Amiloride + Hydrochlorothiazide with alcohol as it may enhance the effect of lightheadedness, low blood pressure, headache, and dizziness.

Pregnancy Maybe Safe

Studies on animal reproduction have failed to demonstrate any risk to the fetus and there are no adequate studies in pregnant women regarding Amiloride + Hydrochlorothiazide.

Driving Not advisable

Do not drive unless you are feeling well. Amiloride + Hydrochlorothiazide may cause side effects such as reduced mental alertness which could affect the ability to concentrate and drive.

Liver Use With Care

Amiloride + Hydrochlorothiazide should be used with caution in patients with pre-existing liver disease

Lactation Limited Data

There is limited data on the safety of Amiloride + Hydrochlorothiazide for breastfeeding. However, the excessive diuretic effect may cause lactation suppression which usage of amiloride alone may not be able to cause this effect.

Written by

Dr. Adeline Carol Peters, Bachelor of Medicine and Bachelor of Surgery (MBBS) — Manipal Academy of Higher Education (MAHE)

Reviewed by

Dr. Mohd Izzat Amir Bin Awang, Doctor of Medicine (MD), University of Mansoura - Manchester