Atovaquone

Uses of Atovaquone

Atovaquone is commonly used to treat Prophylaxis of Pneumocystis Jirovecci Pneumonia, Mild to moderate Pneumocystis Jirovecci Pneumonia

How Atovaquone Works

Atovaquone is an antimalarial or antiprotozoal agent which inhibits complex III of the mitochondrial electron transport chain of Pneumocystis jirovecii. Thus, it inhibits the synthesis of nucleic acids and ATP leading to parasite death.

Side Effects of Atovaquone

Anaemia, Neutropenia, Hyponatremia, Insomnia, Headache, Nausea, Elevated liver enzymes, Hypersensitivity reactions (Throat tightness, angioedema, bronchospasm), Rash, Pruritus, Fever

Information About Atovaquone

Atovaquone is an antiprotozoal agent used to treat and prevent Pneumocystis jirovecii pneumonia and toxoplasmosis in immunocompromised patients in Singapore. Available as a 750mg oral suspension taken twice daily with a fatty meal, it is HSA-registered and available on prescription only in Singapore. It must be taken with food containing fat as bioavailability increases significantly in the presence of dietary lipids — administration without food results in inadequate plasma concentrations and treatment failure. A valid doctor's consultation is required before dispensing. Order Atovaquone online at DoctorOnCall Singapore with same-day delivery available. Speak to a DoctorOnCall physician today to check if Atovaquone is right for you.


Atovaquone is a medication commonly used to prevent and treat certain parasitic and fungal infections, including malaria and Pneumocystis jirovecii pneumonia (PJP). It works by interfering with the energy production processes of microorganisms, helping stop their growth and survival. Atovaquone belongs to a class of medications known as antiparasitic and antimicrobial agents and is widely used in infectious disease treatment and prevention. Find affordable Atovaquone options from trusted brands at DoctorOnCall.

Conclusion

Consult our doctors online for safe and effective use of Atovaquone tailored to your health needs. Find the best prices for affordable Atovaquone tablets and suspensions at DoctorOnCall Singapore.


Warnings

Kidney Safe If Prescribed

Dose adjustment of Atovaquone is not required in patients with renal impairment as it is not excreted renally.

Alcohol Not Advisable

Consumption of alcohol with Atovaquone may be unsafe as both can affect liver enzymes.

Pregnancy Not Safe

Atovaquone may be unsafe to use during pregnancy. There is no information regarding the adverse effects of Atovaquone on the fetus and there are insufficient animal studies that have shown possible risks to the developing fetus. Nevertheless, the benefits from use in pregnant women may be acceptable despite the risk.

Driving Generally Safe

There is no information about the effect of Atovaquone on the ability to drive. Nevertheless, Atovaquone's pharmacological property is not predicted to give detrimental effects on driving.

Liver Limited Data

Atovaquone should be used with caution in patients with liver disease as it is excreted by the liver. Dose adjustment of the medication is not needed. Nevertheless, close monitoring is required following the administration. Please consult your doctor.

Lactation Limited Data

Excretion of Atovaquone in human milk is unknown. Therefore, it is safer to avoid taking Atovaquone during lactation.

Frequently Asked Questions

Written by

Dr. Adeline Carol Peters

, Bachelor of Medicine and Bachelor of Surgery (MBBS) — Manipal Academy of Higher Education (MAHE)

Reviewed by

Dr. Mohd Izzat Amir Bin Awang

, Doctor of Medicine (MD), University of Mansoura - Manchester