Azathioprine

Uses of Azathioprine

Azathioprine is commonly used to treat Autoimmune diseases such as Nephrotic syndrome associated with Lupus Nephritis and Rheumatoid Arthritis, Prevention Of Organ Rejection In Transplant Patients

How Azathioprine Works

Azathioprine inhibits RNA, DNA and purine synthesis and coenzyme function and formation. Thus, it interferes with cellular metabolism and mitosis rendering the immunosuppressive effect.

Side Effects of Azathioprine

Headache, Restlessness, Ireegular Heartbeat, Hallucination, Difficulty In Urination,Paralytic Ileus

Information About Azathioprine

Azathioprine is an immunosuppressant used to treat autoimmune conditions including rheumatoid arthritis, inflammatory bowel disease, and prevent organ transplant rejection in Singapore. Available as a 25mg–50mg oral tablet taken once daily, it is HSA-registered and available on prescription only in Singapore. Testing for thiopurine methyltransferase enzyme activity before initiation is strongly recommended as patients with low or absent enzyme activity face significantly increased risk of severe bone marrow suppression at standard doses. A valid doctor's consultation is required before dispensing. Order Azathioprine online at DoctorOnCall Singapore with same-day delivery available. Speak to a DoctorOnCall physician today to check if Azathioprine is right for you.

Azathioprine is a medication commonly used to suppress the immune system in conditions such as autoimmune diseases and organ transplantation. It works by reducing the activity of immune cells, helping prevent organ rejection and control inflammation caused by an overactive immune response. Azathioprine belongs to a class of medications known as immunosuppressants and is widely used in rheumatology, gastroenterology, and transplant medicine. Find affordable Azathioprine options from trusted brands at DoctorOnCall.

Conclusion

Consult our doctors online for safe and effective use of Azathioprine tailored to your health needs. Find the best prices for affordable Azathioprine tablets and injections at DoctorOnCall Singapore.

Warnings

Kidney High Risk

Azathioprine's toxicity may be enhanced in patients with renal impairment but no controlled studies have supported this statement. Dose adjustment Azathioprine may be needed with haematological monitoring. Please consult your doctor.

Alcohol Safe

It is safe to consume alcohol with Azathioprine as there is no interaction between them.

Pregnancy Not Safe

Azathioprine is unsafe to use during pregnancy. Human and animal studies have shown adverse effects on the fetus such as low birth weight, premature birth and spontaneous abortion. There is also evidence of haematological disorder in neonates whose mother took Azathioprine.

Driving Limited Data

Azathioprine's influence on ability to drive is unknown. Nevertheless, do not drive unless you are feeling well.

Liver Use With Care

Azathioprine is metabolised in the liver. Thus, dose adjustment of Azathioprine may be needed with liver impairment. Please consult your doctor.

Lactation Not Advisable

Azathioprine metabolites such as 6-Mercaptopurine is found in colostrum and breast milk in women receiving the treatment. Thus, Azathioprine should be avoided in lactating women.

Written by

Dr. Adeline Carol Peters, Bachelor of Medicine and Bachelor of Surgery (MBBS) — Manipal Academy of Higher Education (MAHE)

Reviewed by

Dr. Mohd Izzat Amir Bin Awang, Doctor of Medicine (MD), University of Mansoura - Manchester