Calcium Folinate

Uses of Calcium Folinate

Calcium Leucovorin/Calcium Folinate is commonly used to treat Colorectal Cancer, Harmful Effects Of Methotrexate, Methotrexate Toxicity and Megaloblastic Anaemia

How Calcium Folinate Works

Calcium Folinate works by entering the cells and stabilises the binding of 5-dUMP with thymidylate synthetase which enhances the fluorouracil activity while neutralising the effects of a folic acid antagonist such as methotrexate.

Side Effects of Calcium Folinate

Rash, Allergic reaction, Itchiness, Nausea, Vomiting, Fever, Reddening of the skin

Information About Calcium Folinate

Calcium Folinate is a reduced folate used as a rescue agent after high-dose methotrexate therapy and as a biochemical modulator in colorectal cancer treatment in Singapore. Available as an oral tablet or intravenous infusion dosed according to chemotherapy protocol under oncology supervision, it is HSA-registered and available on prescription only in Singapore. It bypasses dihydrofolate reductase inhibition to rescue normal cells from methotrexate toxicity while potentiating fluorouracil's antitumour activity by stabilising the thymidylate synthase inhibitory complex. A valid doctor's consultation is required before dispensing. Order Calcium Folinate online at DoctorOnCall Singapore with same-day delivery available. Speak to a DoctorOnCall physician today to check if Calcium Folinate is right for you.


Calcium Folinate is a medication commonly used to reduce the harmful effects of certain chemotherapy treatments and to treat specific types of anaemia caused by folate deficiency. It works by providing an active form of folic acid that helps support healthy cell growth and protects normal cells from the effects of folate-blocking medications. Calcium Folinate belongs to a class of medications known as folate analogues and rescue agents and is widely used in oncology and supportive care. Find affordable Calcium Folinate options from trusted brands at DoctorOnCall.

Conclusion

Consult our doctors online for safe and effective use of Calcium Folinate tailored to your health needs. Find the best prices for affordable Calcium Folinate tablets and injections at DoctorOnCall Singapore.


Warnings

Kidney Use With Care

Calcium Folinate is excreted through urine and feces thus in patient with renal impairment, dosage adjustment may be needed to avoid toxicity of the compound.

Alcohol Safe

There is no known or previous data on the interaction between alcohol and Calcium Folinate. The side effects profile also suggest there is low likelihood of augmentation of either substances side effects.

Pregnancy Not Safe

Although there are animal studies conducted with higher dose given and showing no adverse effects on reproduction and pregnancy, there are limited human data to suggest the same. It is, therefore, should only be used when the benefits outweigh the risks.

Driving Generally Safe

There is no contraindication for the use of Calcium Folinate before driving. The side effects profile also suggest no contraindication for driving.

Liver Limited Data

Calcium Folinate is metabolised by the liver and in those with liver impairment, dosage adjustment may be required.

Lactation Limited Data

It is not known if Calcium Folinate is excreted into human breastmilk or not. It is therefore should be used with caution.