Clozapine

Uses of Clozapine

Clozapine is commonly used to treat Mania, Schizophrenia, Psychosis in Parkinson Disease and Suicidal Behaviour in Schizophrenia

How Clozapine Works

Clozapine works by inhibiting the dopamine D2 receptor and serotonin type 2A receptor which is effective in controlling symptoms in mania and schizophrenia.

Side Effects of Clozapine

Low blood pressure, Blackout, Seizure, Visual problem, Drooling of saliva, Urinary retention, Fast pulse, Dizziness, Insomnia, Headache

Information About Clozapine

Clozapine is an atypical antipsychotic reserved for treatment-resistant schizophrenia and reducing suicidal behaviour in patients with schizophrenia in Singapore. Available as a 25mg–300mg oral tablet taken once to twice daily with mandatory white blood cell monitoring, it is HSA-registered and available on prescription only in Singapore. Mandatory weekly to monthly full blood count monitoring is non-negotiable throughout therapy as clozapine carries a 1–2% risk of potentially fatal agranulocytosis requiring immediate drug discontinuation if detected. A valid doctor's consultation is required before dispensing. Order Clozapine online at DoctorOnCall Singapore with same-day delivery available. Speak to a DoctorOnCall physician today to check if Clozapine is right for you.


Clozapine is a medication commonly used to treat schizophrenia and certain severe psychiatric conditions that do not respond well to other treatments. It works by affecting dopamine and serotonin activity in the brain, which may help improve thinking, mood, and behaviour. Clozapine belongs to a class of medications known as atypical antipsychotics and is widely used in mental health and psychiatric care. Find affordable Clozapine options from trusted brands at DoctorOnCall.

Conclusion

Consult our doctors online for safe and effective use of Clozapine tailored to your health needs. Find the best prices for affordable Clozapine tablets at DoctorOnCall Singapore.


Warnings

Kidney High Risk

Dosage adjustment is needed in patients with mild to moderate renal impairment and is contraindicated to be used in patients with severe renal impairment.

Alcohol Not Advisable

Clozapine and alcohol consumption may worsen the effects on the central nervous system as their adverse reactions may be compounded.

Pregnancy Maybe Safe

Animal reproductive studies did not suggest any harm on Clozapine use but reports from human studies especially on the use of Clozapine on the third trimester suggest some risk to the neonates. Careful monitoring by specialists is advisable.

Driving Not advisable

It is not advisable to drive when taking Clozapine due to its potential side effects such as headache and dizziness which can affect the ability to drive and concentrate.

Liver Use With Care

Dosage adjustment is needed in patient with mild to moderate hepatic impairment while it is contraindicated to be used in severe hepatic impaired patients.

Lactation Not Advisable

Clozapine has been found in breastmilk according to animal studies and due to its potential serious side effects on the infant, it is not advisable to be used during breastfeeding.

Frequently Asked Questions

Written by

Dr. Adeline Carol Peters

, Bachelor of Medicine and Bachelor of Surgery (MBBS) — Manipal Academy of Higher Education (MAHE)

Reviewed by

Dr. Mohd Izzat Amir Bin Awang

, Doctor of Medicine (MD), University of Mansoura - Manchester

  • Products
    Available medicines with Clozapine
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Prescription Medicine
doctoroncall benefits
Clozaril 100mg Tablet

Starts from

SGD180.15