Colchicine

Uses of Colchicine

Colchicine is commonly used in the treatment of familial Mediterranean fever, hereditary inflammatory disorder, and gout.

How Colchicine Works

Colchicine is an antigout agent which prevents the migration of granulocytes to the inflamed area. It also inhibits the polymerization of β-tubulin into microtubules, which then prevents activation, degranulation, and migration of neutrophils associated with symptoms of gout.

Side Effects of Colchicine

Vomiting, Nausea, Abdominal pain, Diarrhea, Rash, Hemorrhagic gastroenteritis, Hypersensitivity, Myopathy, Arrhythmia, Respiratory failure

Information About Colchicine

Colchicine is an anti-inflammatory agent used to treat and prevent acute gout flares, familial Mediterranean fever, and pericarditis in Singapore. Available as a 0.5mg–1mg oral tablet taken once to twice daily, it is HSA-registered and available on prescription only in Singapore. Patients should stop colchicine immediately and seek medical attention if they develop nausea, vomiting, or diarrhoea — these early gastrointestinal symptoms signal colchicine toxicity and require prompt dose reduction or discontinuation. A valid doctor's consultation is required before dispensing. Order Colchicine online at DoctorOnCall Singapore with same-day delivery available. Speak to a DoctorOnCall physician today to check if Colchicine is right for you.


Colchicine is a medication commonly used to treat and prevent gout attacks by helping reduce inflammation caused by uric acid crystal buildup in the joints. It works by decreasing the activity of inflammatory cells involved in gout flare-ups. Colchicine belongs to a class of medications known as antigout and anti-inflammatory agents and is widely used in gout management and certain inflammatory conditions. Find affordable Colchicine options from trusted brands at DoctorOnCall.

Conclusion

Consult our doctors online for safe and effective use of Colchicine tailored to your health needs. Find the best prices for affordable Colchicine tablets at DoctorOnCall Singapore.


Warnings

Kidney Use With Care

Caution must be practiced while administering Colchicine to patients with mild renal impairment. For moderate renal impairment, dose reduction is required. Colchicine should not be given to patients with severe renal impairment requiring hemodialysis since it cannot be removed by exchange transfusion or dialysis.

Alcohol Not Advisable

Increase risk of gastrointestinal toxicity was reported on the usage of Colchicine with alcohol. Drinking too much alcohol may also increase the level of uric acid in the blood. Thus, minimizing the effects of Colchicine when it is used for prevention of gout attacks.

Pregnancy Not Safe

Animal studies have demonstrated that there is a risk to the fetus, though there are limited human studies. It is best to avoid using Colchicine during pregnancy but potential benefits may allow usage of Colchicine. Woman of childbearing age is advised to use contraception during treatment.

Driving Generally Safe

Colchicine usually does not affect the ability to drive. Do not drive unless you are feeling well.

Liver Limited Data

Colchicine must be used with caution in patients with mild to moderate liver impairment. It is also important to monitor such patients for side effects of Colchicine. For patients with liver impairment who are taking a P-glycoColchicine (P-gp) inhibitor or a strong CYP3A4 inhibitor, Colchicine is contraindicated.

Lactation Limited Data

There is limited data on the safety profile of Colchicine during breastfeeding but it has been shown that Colchicine is excreted in breast milk. Thus, it is recommended to discontinue breastfeeding while on Colchicine.

Frequently Asked Questions