Deferiprone

Uses of Deferiprone

Deferiprone is commonly used to treat iron overload in transfusion dependent Thalassemia.

How Deferiprone Works

Deferiprone is a chelating agent. Its mechanism of action involves binding with ferric ions to form a complex which is then removed via urine.

Side Effects of Deferiprone

Reddish- brown discolouration of urine, Abdominal pain, Nausea, Vomiting, Diarrhea, Dyspepsia, Musculoskeletal pain, Sore throat, Dizziness, Headache, Pruritus, Urticaria.

Information About Deferiprone

Deferiprone is an oral iron chelator used to treat iron overload in patients with thalassaemia major when deferoxamine is inadequate or not tolerated in Singapore. Available as a 500mg oral tablet taken three times daily, it is HSA-registered and available on prescription only in Singapore. Weekly full blood count monitoring is mandatory throughout therapy as deferiprone causes agranulocytosis in approximately 1–2% of patients — treatment must be stopped immediately if neutrophil count falls below 1.5 × 10⁹/L. A valid doctor's consultation is required before dispensing. Order Deferiprone online at DoctorOnCall Singapore with same-day delivery available. Speak to a DoctorOnCall physician today to check if Deferiprone is right for you.


Deferiprone is a medication commonly used to treat iron overload in patients who receive frequent blood transfusions, such as those with thalassaemia. It works by binding to excess iron in the body, allowing it to be removed through urine. Deferiprone belongs to a class of medications known as iron chelating agents and is widely used in haematology and iron overload management. Find affordable Deferiprone options from trusted brands at DoctorOnCall.

Conclusion

Consult our doctors online for safe and effective use of Deferiprone tailored to your health needs. Find the best prices for affordable Deferiprone tablets and oral solutions at DoctorOnCall Singapore.


Warnings

Kidney Use With Care

Although there is no information regarding the effects of renal impairment on the metabolism of Deferiprone, Deferiprone should be used with caution in patients with kidney disease. Dose adjustment of Deferiprone may be needed. Please consult your doctor before using it.

Alcohol Limited Data

Certain food and medications will have interactions with concurrent use of Deferiprone but there is no specific data stating so. Please consult your doctor before using it.

Pregnancy Not Safe

Animal studies have shown embryotoxic and teratogenic potential on the fetus, however, there are limited human studies. The benefits from use in pregnant women may be acceptable despite the risk. Please consult your doctor before using it.

Driving Generally Safe

Deferiprone has negligible effect on your ability to concentrate and drive. You are allowed to drive unless you feel dizzy and headache.

Liver Limited Data

Deferiprone should be used with caution in patients with liver disease by monitoring of liver function. Treatment will be altered if there is a persistent rise in serum ALT. Please consult your doctor before using it.

Lactation Limited Data

Deferiprone is probably unsafe to use during lactation. Deferiprone excretion into human milk is unknown but it is advisable to stop breastfeeding if treatment with Deferiprone is necessary.

Frequently Asked Questions

Written by

Dr. Adeline Carol Peters

, Bachelor of Medicine and Bachelor of Surgery (MBBS) — Manipal Academy of Higher Education (MAHE)

Reviewed by

Dr. Mohd Izzat Amir Bin Awang

, Doctor of Medicine (MD), University of Mansoura - Manchester