Dinoprostone

Uses of Dinoprostone

Dinoprostone is commonly used to treat cervical ripening, induction of labour and augmentation of labour.

How Dinoprostone Works

Dinoprostone is a prostaglandin E2 which exerts its action on uterine smooth muscle, stimulating contraction and cervical relaxation for starting or altering the labour process. It also acts as vasodilator on blood vessels and as a bronchodilator on bronchial muscle.

Side Effects of Dinoprostone

Diarrhea, Nausea, Vomiting, Cardiac arrest, Hypertension, Fever, Hypersensitivity reactions, Uterine hypertonus, Uterine rupture, Abruptio placenta, Rapid cervical dilatation, Uterine hypercontractility with/without foetal bradycardia or foetal distress/altered foetal heart rate (FHR), Neonatal death, Stillbirths, Vaginal irritation, Asthma, Bronchospasm

Information About Dinoprostone

Dinoprostone is a prostaglandin E2 used to induce cervical ripening and labour, and manage postpartum haemorrhage in Singapore. Available as a vaginal gel, pessary, or insert administered under obstetric supervision in a clinical setting, it is HSA-registered and available on prescription only in Singapore. Continuous electronic fetal monitoring is mandatory during dinoprostone administration as uterine hyperstimulation can cause fetal distress — the insert formulation can be rapidly removed if excessive uterine activity occurs. A valid doctor's consultation is required before dispensing. Order Dinoprostone online at DoctorOnCall Singapore with same-day delivery available. Speak to a DoctorOnCall physician today to check if Dinoprostone is right for you.


Dinoprostone is a medication commonly used to induce labour and prepare the cervix for childbirth by helping soften and widen the cervix and stimulate uterine contractions. It works as a prostaglandin that mimics natural substances involved in the labour process. Dinoprostone belongs to a class of medications known as prostaglandins and is widely used in obstetric and maternity care. Find affordable Dinoprostone options from trusted brands at DoctorOnCall.

Conclusion

Consult our doctors online for safe and effective use of Dinoprostone tailored to your health needs. Find the best prices for affordable Dinoprostone vaginal gels, inserts, and suppositories at DoctorOnCall Singapore.


Warnings

Kidney High Risk

Dinoprostone should not be used by patients with active renal disease as it could affect the metabolism or excretion of PGE2. Please consult your doctor before using it.

Alcohol Not Advisable

There may be drug interactions when using Dinoprostone concurrent with drinking alcohol hence It may be unsafe to do so.

Pregnancy Limited Data

Prostin E2 Vaginal Tablets are only used during pregnancy to induce labour. The decision is to be made only after consultation with your doctor and assessment on the pregnancy.

Driving Not advisable

Dinoprostone will initiate labour and driving while in labour will affect your ability to concentrate and drive.

Liver Safe If Prescribed

Dinoprostone should not be used by patients with active hepatic disease as it could affect the metabolism or excretion of PGE2. Please consult your doctor before using it.

Lactation Safe If Prescribed

Dinoprostone can be excreted into human milk and is capable of suppressing lactation, especially during the 1st month of postpartum. Nonetheless, there are no indications for Dinoprostone to be used during breast-feeding period.

Frequently Asked Questions

Written by

Dr. Adeline Carol Peters

, Bachelor of Medicine and Bachelor of Surgery (MBBS) — Manipal Academy of Higher Education (MAHE)

Reviewed by

Dr. Mohd Izzat Amir Bin Awang

, Doctor of Medicine (MD), University of Mansoura - Manchester