Diphenhydramine

Uses of Diphenhydramine

Diphenhydramine is commonly used to treat allergic skin conditions, insomnia, morning sickness, motion sickness, nasal allergy symptoms, vertigo and used as an appetite stimulant.

How Diphenhydramine Works

Diphenhydramine is an antihistamine with anticholinergic and sedative effects. It works by competitively inhibiting histamine H1-receptor in the gastrointestinal and respiratory tract and blood vessels, thus prevents the release of histamine and other inflammatory mediators.

Side Effects of Diphenhydramine

Chest tightness, Hypotension, Palpitations' Difficulty in micturition, Confusion, Dizziness, Drowsiness, Mood imbalance, Sleep disturbances, Restlessness, Sedation, Diarrhea/ constipation

Information About Diphenhydramine

Diphenhydramine is a first-generation antihistamine used to treat allergic reactions, urticaria, motion sickness, and short-term insomnia in Singapore. Available as a 25mg–50mg oral tablet taken every four to six hours or at bedtime for sleep, it is HSA-registered and available on prescription only in Singapore. Due to its strong central anticholinergic and sedating effects, diphenhydramine is not recommended for elderly patients who are at significantly increased risk of confusion, urinary retention, and falls from anticholinergic toxicity. A valid doctor's consultation is required before dispensing. Order Diphenhydramine online at DoctorOnCall Singapore with same-day delivery available. Speak to a DoctorOnCall physician today to check if Diphenhydramine is right for you.


Diphenhydramine is a medication commonly used to relieve allergy symptoms, itching, cold symptoms, and motion sickness, and may also be used as a short-term sleep aid. It works by blocking the action of histamine, a substance in the body that triggers allergic reactions. Diphenhydramine belongs to a class of medications known as antihistamines and is widely used in allergy and symptomatic care. Find affordable Diphenhydramine options from trusted brands at DoctorOnCall.

Conclusion

Consult our doctors online for safe and effective use of Diphenhydramine tailored to your health needs. Find the best prices for affordable Diphenhydramine tablets, capsules, and syrups at DoctorOnCall Singapore.


Warnings

Kidney Use With Care

Diphenhydramine should be used with caution in patients with severe kidney disease. Please consult your doctor.

Alcohol Not Advisable

It is unsafe to consume alcohol with Diphenhydramine.Taking Diphenhydramine with alcohol may have additive CNS depressants.

Pregnancy Maybe Safe

Diphenhydramine may be unsafe to use during pregnancy. Animal studies have not shown adverse effects on the fetus, however, there are limited human studies. The benefits from use in pregnant women may be acceptable despite the risk. Please consult your doctor.

Driving Not advisable

Do not drive unless you are feeling well. Diphenhydramine may cause side effects such as sedation, drowsiness, dizziness, headaches, and psychomotor impairment, all of which could affect your ability to concentrate and drive.

Liver Limited Data

Diphenhydramine should be used with caution in patients with liver disease. Dose adjustment of Diphenhydramine may be needed. Please consult your doctor.

Lactation Limited Data

Diphenhydramine may be excreted in breastmilk. No human data suggests that Diphenhydramine does not represent a significant risk to the baby. Diphenhydramine is not recommended for use during lactation. Please consult your doctor.

Frequently Asked Questions

Written by

Dr. Adeline Carol Peters

, Bachelor of Medicine and Bachelor of Surgery (MBBS) — Manipal Academy of Higher Education (MAHE)

Reviewed by

Dr. Mohd Izzat Amir Bin Awang

, Doctor of Medicine (MD), University of Mansoura - Manchester