Enalapril

Uses of Enalapril

Enalapril is commonly used to treat diabetic kidney disease and heart attack. It is also used to prevent the occurrence of heart attack and stroke.

How Enalapril Works

Enalapril is an angiotensin-converting enzyme (ACE) inhibitor which prevents ACE from converting angiotensin I to angiotensin II. As a result, there is an increase in plasma renin activity and reduce the secretion of aldosterone. All these actions combined will encourage vasodilation and reduce blood pressure.

Side Effects of Enalapril

Headache, Hypotension, Dizziness, Peripheral neuropathy, Insomnia, Vertigo, Persistent dry cough, Nausea, Vomiting, Diarrhea, Rash, Muscle cramps

Information About Enalapril

Enalapril is an ACE inhibitor used to treat hypertension, heart failure, and diabetic nephropathy in Singapore. Available as a 2.5mg–40mg oral tablet taken once to twice daily, it is HSA-registered and available on prescription only in Singapore. The first dose should be taken at bedtime or under supervision as symptomatic hypotension can occur upon initiation, particularly in salt-depleted or volume-depleted patients — patients who develop dry cough may be switched to an angiotensin receptor blocker. A valid doctor's consultation is required before dispensing. Order Enalapril online at DoctorOnCall Singapore with same-day delivery available. Speak to a DoctorOnCall physician today to check if Enalapril is right for you.


Enalapril is a medication commonly used to treat high blood pressure, heart failure, and certain kidney conditions by helping relax blood vessels and improve blood flow. It works by blocking the production of angiotensin II, a substance that causes blood vessels to narrow. Enalapril belongs to a class of medications known as angiotensin-converting enzyme (ACE) inhibitors and is widely used in cardiovascular and renal care. Find affordable Enalapril options from trusted brands at DoctorOnCall.

Conclusion

Consult our doctors online for safe and effective use of Enalapril tailored to your health needs. Find the best prices for affordable Enalapril tablets and oral solutions at DoctorOnCall Singapore.


Warnings

Kidney Use With Care

In patients with renal impairment, the dosage of Enalapril needs to be adjusted depending on the renal function, particularly the patient's creatinine clearance. It is also important to do routine monitoring of the renal function during the treatment for such patients. There are also cases of renal failure reported in regards to Enalapril and most occur in patients with severe heart failure or underlying renal disease. When treated early, renal failure caused by Enalapril is reversible.

Alcohol Not Advisable

It is not advisable to consume Enalapril with alcohol because they can have an additive hypotensive effect.

Pregnancy Not Safe

There is evidence of human studies in which Enalapril possesses risks to the fetus even though potential benefits may warrant the usage during pregnancy. Any ACE inhibitor should not be started during pregnancy and unless continuous therapy with ACE inhibitor is indicated, it is inevitable that antihypertensive need to be changed to other alternatives with known safety profile in pregnancy. Specifically, during the second and third trimester of pregnancy, Enalapril can cause human fetotoxicity and neonatal toxicity, thus it should be avoided at all cost.

Driving Generally Safe

Enalapril usually does not affect the ability to drive. Do not drive unless you are feeling well.

Liver Limited Data

ACE inhibitor could be associated with cholestatic jaundice or hepatitis which then progresses to fulminant hepatic necrosis or death. If the patient develops jaundice or a significant increase of liver enzymes following usage of Enalapril, it is best to discontinue Enalapril and advice the patient to seek appropriate medical attention.

Lactation Limited Data

There is limited data on the safety profile of Enalapril in breastfeeding. However, few studies have shown that Enalapril is excreted in very low concentrations in breast milk. Although this could be deemed as insignificant, the usage of Enalapril during breastfeeding is not advisable for preterm infants and early delivery period because of the potential risk of cardiovascular and renal effects.

Frequently Asked Questions

Written by

Dr. Adeline Carol Peters

, Bachelor of Medicine and Bachelor of Surgery (MBBS) — Manipal Academy of Higher Education (MAHE)

Reviewed by

Dr. Mohd Izzat Amir Bin Awang

, Doctor of Medicine (MD), University of Mansoura - Manchester

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Enahexal 20mg Tablet
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Acetec 20mg Tablet

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