Eplerenone

Uses of Eplerenone

Eplerenone is commonly used to treat Heart Failure and Hypertension.

How Eplerenone Works

The pathway of renin-angiotensin-aldosterone-system regulates blood pressure by renal reabsorption of sodium, vascular remodelling, water retention and the endothelium. Eplerenone inhibits RAAS involving the kidney, digestive system, cardiovascular tissue and brain tissue.

Side Effects of Eplerenone

Cough, Difficulty sleeping (insomnia), Dizziness, Syncope, Headache, Left ventricular failure, Atrial fibrillation, Decrease in blood pressure (hypotension), Diarrhea, Nausea, Constipation, Vomiting, Rash, Muscle Spasm, Kidney dysfunction

Information About Eplerenone

Eplerenone is a selective mineralocorticoid receptor antagonist used to treat hypertension and reduce cardiovascular mortality following acute myocardial infarction with heart failure in Singapore. Available as a 25mg–50mg oral tablet taken once daily, it is HSA-registered and available on prescription only in Singapore. Its selectivity for mineralocorticoid over progesterone and androgen receptors avoids the gynaecomastia and sexual dysfunction associated with the non-selective aldosterone antagonist spironolactone, improving tolerability in male patients. A valid doctor's consultation is required before dispensing. Order Eplerenone online at DoctorOnCall Singapore with same-day delivery available. Speak to a DoctorOnCall physician today to check if Eplerenone is right for you.


Eplerenone is a medication commonly used to treat high blood pressure and heart failure by helping reduce fluid retention and decrease strain on the heart. It works by blocking the action of aldosterone, a hormone that causes the body to retain salt and water. Eplerenone belongs to a class of medications known as aldosterone antagonists and potassium-sparing diuretics and is widely used in cardiovascular care. Find affordable Eplerenone options from trusted brands at DoctorOnCall.

Conclusion

Consult our doctors online for safe and effective use of Eplerenone tailored to your health needs. Find the best prices for affordable Eplerenone tablets at DoctorOnCall Singapore.


Warnings

Kidney Use With Care

Eplerenone should be used with caution in patients with mild to moderate kidney disease. Dose adjustment of Eplerenone may be needed. Please consult your doctor before using it. Use of Eplerenone is not recommended in patients with severe kidney disease.

Alcohol Not Advisable

It is unsafe to consume alcohol with Eplerenone as it may aggravate lowering of your blood pressure. With hypotension, you may experience headache, dizziness, lightheadedness, fainting, and/or changes in pulse or heart rate.

Pregnancy Maybe Safe

Eplerenone may be unsafe to use during pregnancy. Animal studies have shown adverse effects on the fetus, however, there are limited human studies. Please consult your doctor before using it.

Driving Generally Safe

Eplerenone may cause side effects such as dizziness, headaches or nausea, all of which could affect your ability to concentrate and drive. Do not drive unless you are feeling well.

Liver Limited Data

Eplerenone should be used with caution in patients with mild-to-moderate liver disease. Dose adjustment of Eplerenone may be needed. Please consult your doctor before using it. Use of Eplerenone is not recommended in patients with severe kidney disease.

Lactation Limited Data

Eplerenone is excreted into the breastmilk of mammals in animal studies but is largely unknown in human studies. Due to its potential adverse effect on feeding infant, the decision to continue Eplerenone or withhold breastfeeding is to be done after consultation with your doctor.

Frequently Asked Questions