Everolimus

Uses of Everolimus

Everolimus is commonly used to treat advanced renal cell carcinoma, prevention of organ rejection in patients receiving a kidney, hepatic or heart transplant as well as in neuroendocrine tumours.

How Everolimus Works

Everolimus is a selective mTOR inhibitor. mTOR is a mediator in the signalling pathway which is known to be upregulated in a number of human cancers. Therefore, the growth and proliferation of tumour cells, vascular smooth muscle and fibroblasts is inhibited. Everolimus also acts as an immunosuppressant by inhibiting T-cell proliferation.

Side Effects of Everolimus

Stomatitis, Rash, Fatigue, Diarrhea, Nausea, Reduced appetite, Low red blood cell, Pneumonitis, Peripheral oedema, Increased blood sugar level, Loss of weight, Increased blood cholesterol, Nose bleed, Cough, Headache

Information About Everolimus

Everolimus is an mTOR inhibitor used to treat advanced renal cell carcinoma, hormone receptor-positive breast cancer, and neuroendocrine tumours in Singapore. Available as a 2.5mg–10mg oral tablet taken once daily at the same time with or without food, it is HSA-registered and available on prescription only in Singapore. Patients must avoid grapefruit, grapefruit juice, and Seville oranges throughout therapy as CYP3A4 inhibition significantly increases everolimus blood levels, risking dose-dependent toxicity including stomatitis, pneumonitis, and immunosuppression. A valid doctor's consultation is required before dispensing. Order Everolimus online at DoctorOnCall Singapore with same-day delivery available. Speak to a DoctorOnCall physician today to check if Everolimus is right for you.

Everolimus is a medication commonly used to treat certain types of cancer, prevent organ transplant rejection, and manage specific rare genetic disorders. It works by inhibiting the mTOR pathway, which helps slow abnormal cell growth, reduce tumour progression, and suppress immune system activity when needed. Everolimus belongs to a class of medications known as mTOR inhibitors and is widely used in oncology and transplant medicine. Find affordable Everolimus options from trusted brands at DoctorOnCall.

Conclusion

Consult our doctors online for safe and effective use of Everolimus tailored to your health needs. Find the best prices for affordable Everolimus tablets and dispersible tablets at DoctorOnCall Singapore.

Warnings

Kidney High Risk

Everolimus should be used with caution in patients with kidney disease as cases of failure have been reported in patients treated with Everolimus. Dose adjustment and monitoring of renal function may be needed. Please consult your doctor before using it.

Alcohol Not Advisable

It is generally not advisable to consume alcohol with Everolimus or any chemotherapy medication. Please consult your doctor before using it.

Pregnancy Not Safe

Everolimus may be unsafe to use during pregnancy. Animal studies have shown adverse effects on the fetus, however, there are limited human studies. The benefits from use in pregnant women may be acceptable despite the risk. Please consult your doctor before using it.

Driving Generally Safe

Everolimus may cause side effects such as dizziness, headaches, nausea or tiredness, all of which could affect your ability to concentrate and drive. Do not drive unless you are feeling well.

Liver Use With Care

Everolimus should be used with caution in patients with liver disease. Dose adjustment of Everolimus may be needed. Please consult your doctor before using it.

Lactation Not Advisable

Animal studies showed that Everolimus and its metabolites are excreted into breast milk. However, much is unknown about its excretion into human breast milk or its potential risks to the feeding baby. Hence, women on Everolimus is not advised to breastfeed. Please consult your doctor before using it.