Fludarabine

Uses of Fludarabine

Fludarabine is commonly used to treat Blood Cancer, Blood Cancer Chronic Lymphocytic Leukemia, Non Hodgkin Lymphoma Nhl

How Fludarabine Works

Fludarabine is a purine antagonist. It works by inhibiting alpha-DNA polymerase, ribonucleotide reductase and DNA primase in DNA synthesis hence leading to cell death.

Side Effects of Fludarabine

Skin cancer, Confusion, Seizure, Chest pain, Nausea, Vomiting, Diarrhea, Cough, Shortness of breath, Painful urinating

Information About Fludarabine

Fludarabine is a purine nucleoside analogue used to treat chronic lymphocytic leukaemia and low-grade non-Hodgkin's lymphoma in Singapore. Available as a 10mg oral tablet taken for five consecutive days per cycle or as an intravenous infusion under oncology supervision, it is HSA-registered and available on prescription only in Singapore. Its profound lymphocyte-depleting effects necessitate Pneumocystis jirovecii pneumonia prophylaxis throughout therapy and for several months after completion, as CD4+ T-cell recovery can take years. A valid doctor's consultation is required before dispensing. Order Fludarabine online at DoctorOnCall Singapore with same-day delivery available. Speak to a DoctorOnCall physician today to check if Fludarabine is right for you.

Fludarabine is a medication commonly used to treat certain types of blood cancers, particularly chronic lymphocytic leukaemia (CLL) and other haematological malignancies. It works by interfering with the DNA of cancer cells, helping stop their growth and multiplication. Fludarabine belongs to a class of medications known as antimetabolite chemotherapy agents and is widely used in oncology and haematology care. Find affordable Fludarabine options from trusted brands at DoctorOnCall.

Conclusion

Consult our doctors online for safe and effective use of Fludarabine tailored to your health needs. Find the best prices for affordable Fludarabine tablets and injections at DoctorOnCall Singapore.

Warnings

Kidney High Risk

Dosage adjustment is needed in patients with mild to moderate renal impairment and is contraindicated to be used in patients with severe renal impairment.

Alcohol Limited Data

There is no clear contraindication of the consumption of alcohol when taking Fludarabine

Pregnancy Not Safe

Animal studies clearly showed teratogenicity and harmful effects on the fetal development. Fludarabine should not be used during pregnancy regardless of which trimester stage unless there is no other form of treatment besides Fludarabine.

Driving Not advisable

Fludarabine is generally safe to be used before driving but caution should be taken if the user feels fatigued or having visual disturbance after taking Fludarabine.

Liver Use With Care

Although there is no clear contraindication nor dosage adjustment needed for hepatic impaired patients, caution should still be taken since the patient may take any other medications as well.

Lactation Not Advisable

It is not known fully whether Fludarabine or its metabolites pass into breastmilk or not. Due to its potential toxicity and effects on the breastfeeding infant, breastfeeding is contraindicated during the treatment course.

Written by

Dr. Adeline Carol Peters, Bachelor of Medicine and Bachelor of Surgery (MBBS) — Manipal Academy of Higher Education (MAHE)

Reviewed by

Dr. Mohd Izzat Amir Bin Awang, Doctor of Medicine (MD), University of Mansoura - Manchester