Gefitinib

Uses of Gefitinib

Gefitinib is commonly used to treat Non-Small Cell Lung Cancer

How Gefitinib Works

Gefitinib is a tyrosine kinase inhibitor which works by preventing autophosphorylation of tyrosine residue associated with the EGFR receptor. This, in turn, prevents the replication of cancer and non-cancer cells.

Side Effects of Gefitinib

Itchiness, Skin rashes, Nose bleed, Blood in urine, Dry mouth, Nausea, Vomiting, Eye pain, Fever, Diarrhea,

Information About Gefitinib

Gefitinib is a first-generation EGFR tyrosine kinase inhibitor used to treat EGFR mutation-positive non-small cell lung cancer in Singapore. Available as a 250mg oral tablet taken once daily with or without food, it is HSA-registered and available on prescription only in Singapore. Tumour EGFR mutation testing is mandatory before initiation as gefitinib is only effective in patients with sensitising EGFR mutations — wild-type EGFR tumours show no benefit and may have inferior outcomes compared to chemotherapy. A valid doctor's consultation is required before dispensing. Order Gefitinib online at DoctorOnCall Singapore with same-day delivery available. Speak to a DoctorOnCall physician today to check if Gefitinib is right for you.

Gefitinib is a medication commonly used to treat certain types of non-small cell lung cancer (NSCLC) that have specific epidermal growth factor receptor (EGFR) mutations. It works by blocking EGFR activity, which helps slow or stop the growth and spread of cancer cells. Gefitinib belongs to a class of medications known as EGFR inhibitors and is widely used in targeted cancer therapy and oncology care. Find affordable Gefitinib options from trusted brands at DoctorOnCall.

Conclusion

Consult our doctors online for safe and effective use of Gefitinib tailored to your health needs. Find the best prices for affordable Gefitinib tablets at DoctorOnCall Singapore.

Warnings

Kidney Use With Care

There is no dosage adjustment recommended for those with renal impairment with renal clearance more than 20ml/min. Caution and dosage adjustment is advisable for those with renal clearance less than 20ml/min.

Alcohol Safe

There is no clear contraindication on the consumption of alcohol when taking Gefitinib..

Pregnancy Not Safe

Animal studies have shown reproductive toxicity when using Gefitinib but there are limited human data available to conclude the safety profile during pregnancy. It is not recommended to be used during pregnancy due to its potential harm on the fetal development.

Driving Generally Safe

It is generally safe to drive when taking Gefitinib but caution should still be taken if some adverse effects of Gefitinib affects the ability and concentration to drive.

Liver Use With Care

Dosage adjustment is recommended for people with mild to moderate liver impairment with close monitoring and is contraindicated if the liver functions severely deteriorated.

Lactation Not Advisable

Gefitinib is excreted into rats breastmilk but no human data available to confim this. It is therefore not advisable for women undergoing treatment with Gefitinib to breastfeed due to its potential toxicity.

Written by

Dr. Adeline Carol Peters, Bachelor of Medicine and Bachelor of Surgery (MBBS) — Manipal Academy of Higher Education (MAHE)

Reviewed by

Dr. Mohd Izzat Amir Bin Awang, Doctor of Medicine (MD), University of Mansoura - Manchester