Glibenclamide

Uses of Glibenclamide

Glibenclamide is commonly used in the treatment of Type 2 Diabetes Mellitus

How Glibenclamide Works

Glibenclamide is a sulfonylurea, an antidiabetic drug. It works by increasing the amount of insulin the pancreas makes, therefore creating a low blood glucose environment in the body. This helps insulin work more efficiently in the peripheral organs and reduce glucose production by the liver.

Side Effects of Glibenclamide

Weight Gain, Nausea, Heartburn, Diarrhea, Rashes, Skin itch, Joint pain, Muscle pain, Low blood glucose.

Information About Glibenclamide

Glibenclamide is a second-generation sulphonylurea used to treat type 2 diabetes in adults requiring oral antidiabetic therapy in Singapore. Available as a 2.5mg–5mg oral tablet taken once to twice daily with meals, it is HSA-registered and available on prescription only in Singapore. Due to its long duration of action and active metabolites, glibenclamide carries a higher risk of prolonged hypoglycaemia than shorter-acting sulphonylureas — it is not recommended for elderly patients or those with renal impairment. A valid doctor's consultation is required before dispensing. Order Glibenclamide online at DoctorOnCall Singapore with same-day delivery available. Speak to a DoctorOnCall physician today to check if Glibenclamide is right for you.


Glibenclamide is a medication commonly used to help manage type 2 diabetes by lowering blood sugar levels. It works by stimulating the pancreas to release more insulin, which helps the body utilise glucose more effectively. Glibenclamide belongs to a class of medications known as sulfonylureas and is widely used in diabetes management. Find affordable Glibenclamide options from trusted brands at DoctorOnCall.

Conclusion

Consult our doctors online for safe and effective use of Glibenclamide tailored to your health needs. Find the best prices for affordable Glibenclamide tablets at DoctorOnCall Singapore.


Warnings

Kidney Use With Care

Glibenclamide requires dose adjustment for patients with mild to moderate kidney disease as it is partially excreted in the urine. Please consult your doctor. Patients with severe kidney disease are contraindicated from taking Glibenclamide.

Alcohol Not Advisable

Glibenclamide is known to have an effect similar to a drug called disulfiram, which is used to curb chronic alcoholism. It renders the patient being acutely sensitive to alcohol and feeling unwell.

Pregnancy Not Safe

Glibenclamide may be unsafe to use during pregnancy as animal studies have shown adverse effects on the foetus and human studies also showed some adverse effect. Therefore, please consult your doctor to discuss the benefits over the risks of taking sulfonylurea due to their chance of having too low blood sugar.

Driving Generally Safe

Glibenclamide usually does not affect the ability to drive. Do not drive unless you are feeling well.

Liver Use With Care

Glibenclamide may require dose adjustments for patients with liver disease so please consult your doctor before starting Glibenclamide. However, patients with severe liver disease are contraindicated from taking Glibenclamide.

Lactation Not Advisable

Glibenclamide being excreted into the breast milk has not been made certain but the risk of having a baby with too low blood sugar cannot be excluded. Therefore, it isn't safe for breastfeeding.

Frequently Asked Questions

Written by

Dr. Adeline Carol Peters

, Bachelor of Medicine and Bachelor of Surgery (MBBS) — Manipal Academy of Higher Education (MAHE)

Reviewed by

Dr. Mohd Izzat Amir Bin Awang

, Doctor of Medicine (MD), University of Mansoura - Manchester