Can I become resistant to isoniazid?

Resistance can happen if the bacteria gets modified in your body and stops reacting to the medications. This is called drug resistance. Drug resistance is uncommon if isoniazid is used with other tuberculosis medication.

Does isoniazid affect birth control?

isoniazid has no known integration with birth control medications. However, combination treatments for tuberculosis containing rifampin is said to have some decrease in effectiveness of oral contraceptives.

Is isoniazid bacteriostatic or bactericidal?

isoniazid is known to be a bacteriostatic medication. isoniazid stops the growth of bacteria by disrupting the formation of protective outer cell which is essential for the bacteria to grow.

Isoniazid

Uses of Isoniazid

Isoniazid is commonly used in the treatment of Tuberculosis (TB).

How Isoniazid Works

Isoniazid is an anti-tuberculosis agent. It works by inhibiting the synthesis of mycolic acids in acid-fast bacilli and disrupts the cell wall of the mycobacterium that causes Tuberculosis.

Side Effects of Isoniazid

Nausea, Vomiting, Dry mouth, Constipation, Dizziness, Hyperreflexia, Blurring of vision, Dyspnea, Urinary retention, Hypersensitivity reactions

Information About Isoniazid

Isoniazid is a bactericidal antimycobacterial agent used as the cornerstone of tuberculosis treatment and latent TB prophylaxis in Singapore. Available as a 100mg–300mg oral tablet taken once daily on an empty stomach, it is HSA-registered and available on prescription only in Singapore. Pyridoxine (vitamin B6) supplementation at 10–25mg daily is recommended alongside isoniazid to prevent peripheral neuropathy, which occurs through isoniazid-mediated depletion of pyridoxine-dependent enzyme cofactors. A valid doctor's consultation is required before dispensing. Order Isoniazid online at DoctorOnCall Singapore with same-day delivery available. Speak to a DoctorOnCall physician today to check if Isoniazid is right for you.

Isoniazid is an antibiotic medication commonly used to treat and prevent tuberculosis (TB). It works by inhibiting the formation of essential components of the bacterial cell wall, helping stop the growth and spread of Mycobacterium tuberculosis. Isoniazid belongs to a class of medications known as antitubercular agents and is widely used in tuberculosis treatment and prevention programs. Find affordable Isoniazid options from trusted brands at DoctorOnCall.

Conclusion

Consult our doctors online for safe and effective use of Isoniazid tailored to your health needs. Find the best prices for affordable Isoniazid tablets and oral formulations at DoctorOnCall Singapore.

Warnings

Kidney Use With Care

Isoniazid should be used with caution in patients with severe kidney disease. Dose adjustment of Isoniazid is necessary. Please consult your doctor.

Alcohol Not Advisable

It is unsafe to consume alcohol with Isoniazid. Taking Isoniazid with alcohol may cause a reduction in the efficacy of the Isoniazid. It may also increase the risk of developing hepatic damage and peripheral neuropathy.

Pregnancy Not Safe

Isoniazid may be unsafe to use during pregnancy. Animal studies have shown the use of the Isoniazid may cause adverse effects on the fetus. However, there are limited well-controlled human studies. The benefits from the use of Isoniazid in pregnant women may be acceptable despite the risk. Please consult your doctor.

Driving Generally Safe

Isoniazid usually does not affect the ability to drive. Do not drive unless you are feeling well.

Liver Use With Care

Isoniazid is contraindicated in patients with acute liver disease and with a history of Isoniazid-associated hepatic injury. Frequent monitoring of liver function tests and dose adjustment is necessary. Please consult your doctor.

Lactation Not Advisable

Isoniazid is probably unsafe to use during lactation. Isoniazid is excreted into human breast milk hence should be avoided during lactation.

Frequently Asked Questions

Written by

Dr. Adeline Carol Peters, Bachelor of Medicine and Bachelor of Surgery (MBBS) — Manipal Academy of Higher Education (MAHE)

Reviewed by

Dr. Mohd Izzat Amir Bin Awang, Doctor of Medicine (MD), University of Mansoura - Manchester