Leflunomide

Uses of Leflunomide

Leflunomide is commonly used to treat Psoriatic Arthritis, Rheumatoid Arthritis

How Leflunomide Works

Leflunomide is an immunomodulating agent and DMARD. It gives antiproliferative and anti-inflammatory effects by inhibiting DNA building block synthesis via inhibition of dihydroorotate dehydrogenase enzyme activity.

Side Effects of Leflunomide

Low white cell count, Mild allergic reactions, Increased CPK enzyme, Headache, Dizziness, Peripheral neuropathy, Nausea and vomiting , Abdominal pain, Loss of appetite, Weight loss

Information About Leflunomide

Leflunomide is a disease-modifying antirheumatic drug used to treat rheumatoid arthritis and psoriatic arthritis in Singapore. Available as a 10mg–20mg oral tablet taken once daily, it is HSA-registered and available on prescription only in Singapore. Its active metabolite teriflunomide has an exceptionally long half-life of several weeks due to enterohepatic recirculation — cholestyramine or activated charcoal accelerated elimination procedures are required in case of toxicity or when switching to teratogenic medications. A valid doctor's consultation is required before dispensing. Order Leflunomide online at DoctorOnCall Singapore with same-day delivery available. Speak to a DoctorOnCall physician today to check if Leflunomide is right for you.


Leflunomide is a medication commonly used to treat rheumatoid arthritis and other autoimmune conditions by helping reduce inflammation, joint damage, and disease progression. It works by suppressing the activity of certain immune cells involved in the inflammatory process. Leflunomide belongs to a class of medications known as disease-modifying antirheumatic drugs (DMARDs) and is widely used in rheumatology care. Find affordable Leflunomide options from trusted brands at DoctorOnCall.

Conclusion

Consult our doctors online for safe and effective use of Leflunomide tailored to your health needs. Find the best prices for affordable Leflunomide tablets at DoctorOnCall Singapore.


Warnings

Kidney High Risk

No dosage adjustment of Leflunomide in patients with mild kidney disease. Nevertheless, use of Leflunomide is contraindicated in patients with moderate to severe kidney disease as adverse effects cannot be excluded due to lacking clinical studies.

Alcohol Not Advisable

It is unsafe to consume alcohol with Leflunomide as there are higher risk of liver toxicity.

Pregnancy Limited Data

Leflunomide is unsafe to use during pregnancy as it can cause serious birth defects. Contraception must be used up to 2 years after treatment to avoid the adverse effects.

Driving Not advisable

Leflunomide may cause side effects such as dizziness, headaches, nausea or tiredness, all of which could affect your ability to concentrate and drive.Therefore, patients should restrain themselves from taking the medication whilst driving.

Liver Use With Care

Liver function should be tested prior to administration of Leflunomide as it can cause liver impairment. Hence, it should not be used with other medications that can cause liver toxicity. Frequent liver function monitoring is required.

Lactation Not Advisable

Leflunomide should not be used during lactation as animal studies indicate that Leflunomide or its metabolites pass into breast milk.

Frequently Asked Questions