Lopinavir

Uses of Lopinavir

Lopinavir is commonly used to treat HIV Infection

How Lopinavir Works

Lopinavir is an antiretroviral agent which is used in combination with Ritonavir. It inhibits an enzyme, HIV protease to be incapable of processing the polyprotein precursor. This leads to the production of non-infectious and immature HIV particles.

Side Effects of Lopinavir

Diarrhea, Abdominal pain, Headache, Indigestion (Dyspepsia), Vomiting, Palpitation, Agitation and confusion, Tinnitus, Acne, Dry skin and skin discoloration

Information About Lopinavir

Lopinavir is an HIV protease inhibitor used exclusively in combination with ritonavir as a pharmacokinetic booster in antiretroviral therapy in Singapore. Available only as a fixed combination with ritonavir, it is HSA-registered and available on prescription only in Singapore. Without ritonavir boosting, lopinavir plasma levels fall below therapeutic concentrations due to extensive CYP3A4 metabolism — the ritonavir component acts purely as a metabolic inhibitor rather than a therapeutic antiviral agent in this combination. A valid doctor's consultation is required before dispensing. Order Lopinavir online at DoctorOnCall Singapore with same-day delivery available. Speak to a DoctorOnCall physician today to check if Lopinavir is right for you.

Lopinavir is an antiviral medication commonly used as part of combination therapy to treat HIV infection by helping reduce the amount of virus in the body and support immune system function. It works by inhibiting the HIV protease enzyme, which prevents the virus from maturing and multiplying effectively. Lopinavir belongs to a class of medications known as protease inhibitors and is widely used in antiretroviral therapy for HIV management. Find affordable Lopinavir options from trusted brands at DoctorOnCall.

Conclusion

Consult our doctors online for safe and effective use of Lopinavir tailored to your health needs. Find the best prices for affordable Lopinavir tablets, capsules, and oral solutions at DoctorOnCall Singapore.

Warnings

Kidney High Risk

Lopinavir is contraindicated in patients with kidney failure.

Alcohol Safe

It is safe to consume alcohol with Lopinavir as there is no known drug interactions.

Pregnancy Limited Data

Lopinavir may be safe to use during pregnancy if it is clinically indicated. Human studies have not shown any adverse effects to fetal formation.

Driving Limited Data

There is no information regarding the effects of Lopinavir whilst driving. However, patients should be informed that there is a risk of nausea when taking Lopinavir.

Liver Limited Data

In patients with liver disease, the use of Lopinavir is contraindicated.

Lactation Limited Data

It is not known whether Lopinavir is excreted in human milk. Adverse risk effect cannot be excluded. Therefore, it is not recommended for Lopinavir to be used during lactation. Also, mothers with HIV should avoid breastfeeding their babies to avoid transmission.

Written by

Dr. Adeline Carol Peters, Bachelor of Medicine and Bachelor of Surgery (MBBS) — Manipal Academy of Higher Education (MAHE)

Reviewed by

Dr. Mohd Izzat Amir Bin Awang, Doctor of Medicine (MD), University of Mansoura - Manchester