Lumefantrine

Uses of Lumefantrine

Lumefantrine is commonly used to treat Cerebral Malaria, Malaria

How Lumefantrine Works

Lumefantrine is an antimalarial medication. It interferes with the conversion of a toxic intermediate, haem to the nontoxic haemozoin. It also inhibits nucleic acid and protein synthesis. The exact mechanism of action of Lumefantrine is still unknown.

Side Effects of Lumefantrine

Decreased appetite, Difficulty sleeping (insomnia), Sleep disorders, Headache, Dizziness, Palpitations, Pins and needles, Cough, Diarrhea, Rash and pruritus

Information About Lumefantrine

Lumefantrine is an antimalarial arylaminoalcohol used exclusively in fixed combination with artemether to treat uncomplicated Plasmodium falciparum malaria in Singapore. Available as a fixed-dose oral tablet (120mg lumefantrine) taken with fatty food over three days, it is HSA-registered and available on prescription only in Singapore. Co-administration with a fatty meal is essential as lumefantrine's oral bioavailability increases up to 16-fold in the fed state — inadequate fat intake significantly reduces plasma drug concentrations and risks treatment failure. A valid doctor's consultation is required before dispensing. Order Lumefantrine online at DoctorOnCall Singapore with same-day delivery available. Speak to a DoctorOnCall physician today to check if Lumefantrine is right for you.


Lumefantrine is an antimalarial medication commonly used in combination with other antimalarial agents to treat uncomplicated malaria caused by Plasmodium parasites. It works by interfering with the parasite’s ability to survive and multiply within red blood cells. Lumefantrine belongs to a class of medications known as antimalarial agents and is widely used in infectious disease and travel medicine care. Find affordable Lumefantrine options from trusted brands at DoctorOnCall.

Conclusion

Consult our doctors online for safe and effective use of Lumefantrine tailored to your health needs. Find the best prices for affordable Lumefantrine tablets and combination antimalarial formulations at DoctorOnCall Singapore.


Warnings

Kidney Use With Care

Lumefantrine should be used with caution in patients with severe kidney disease. ECG and potassium monitoring is required in patients with severe kidney disease. No dose adjustment of Lumefantrine may be needed if patient has mild to moderate kidney disease.

Alcohol Safe

It is safe to consume alcohol with Lumefantrine as there is no known drug interaction.

Pregnancy Not Safe

Lumefantrine may be unsafe to use during pregnancy. Animal studies have shown adverse effects on the fetus, however, there are limited human studies. The usage of Lumefantrine in pregnant women may be acceptable despite the risk. Please consult your doctor.

Driving Not advisable

Do not drive unless you are feeling well. Patients should be warned that Lumefantrine may cause side effects such as dizziness and headache which could affect your ability to concentrate and drive.

Liver Limited Data

Lumefantrine should be used with caution in patients with severe liver disease. Nevertheless, no dose adjustment of Lumefantrine may be needed in mild to moderate liver disease.

Lactation Limited Data

There is no information regarding the excretion of Lumefantrine in human breast milk. Therefore, adverse effect of Lumefantrine can be excluded. It is probably unsafe to use during lactation.

Frequently Asked Questions