Am I at a high risk of developing deep vein thrombosis (DVT) while taking medroxyprogesterone acetate?

There is an increased risk of developing DVT while taking medroxyprogesterone acetate especially in the first year or after restarting medroxyprogesterone acetate following a break of 4 weeks or more. However, this risk increases with age an in the presence of other risk factors such as obesity. The risk of developing DVT also depends on the type of progestogen. Speak to your doctor or pharmacist if you develop swelling in one leg, pain or tenderness in one leg when walking, increased warmth in the leg or red or discoloured skin on the leg.

Does medroxyprogesterone acetate protect against sexually transmitted infections (STIs)?

The pill does not protect you against STIs. You are recommended to use a condom as well to protect you against STIs.

Does a withdrawal bleed always occur?

A withdrawal bleed often occurs during the 7 day interval of hormone-free or sugar pills. However, some women do not experience withdrawal bleeds during the hormone-free period. If you have been taking your COC correctly, it should not be of a concern but if you have not been taking them according to the directions, there may be a chance that pregnancy has occured.

What if I vomit after taking a dose of medroxyprogesterone acetate?

If you vomit 3-4 hours after taking your dose of an active pill, it is considered a missed dose. You should follow the instructions on how to manage a missed dose to ensure you are still protected.

Medroxyprogesterone Acetate

Uses of Medroxyprogesterone Acetate

Medroxyprogesterone Acetate is commonly used in the treatment of Abnormal Uterine Bleeding, Breast Cancer, Endometriosis and Post Menopausal Osteoporosis. It is also used to relieve heavy menstrual bleeding. Medroxyprogesterone Acetate is also used in hormone replacement therapy and contraception.

How Medroxyprogesterone Acetate Works

Medroxyprogesterone Acetate is a synthetic form of progesterone which converts the proliferative phase of the endometrium into secretory phase but without the presence of estrogenic activity and minimal androgenic effect. It also prevents follicular maturation and ovulation hence it’s used as contraception.

Side Effects of Medroxyprogesterone Acetate

Dysfunctional uterine bleeding (irregular menstrual cycle, spotting, ) Fatigue, Insomnia, Edema, Depression, Dizziness, Headache, Nausea, Vomiting, Breast tenderness, Weight gain or loss, Pain at injection site

Information About Medroxyprogesterone Acetate

Medroxyprogesterone Acetate is a synthetic progestogen used for contraception, hormone replacement therapy, endometriosis, and certain gynaecological cancers in Singapore. Available as a 2.5mg–10mg oral tablet taken cyclically or continuously, or as a 150mg depot intramuscular injection every three months, it is HSA-registered and available on prescription only in Singapore. The injectable depot form provides highly effective long-term contraception for three months per injection — return of fertility may be delayed up to 18 months after discontinuation compared to other hormonal contraceptive methods. A valid doctor's consultation is required before dispensing. Order Medroxyprogesterone Acetate online at DoctorOnCall Singapore with same-day delivery available. Speak to a DoctorOnCall physician today to check if Medroxyprogesterone Acetate is right for you.

Medroxyprogesterone Acetate is a medication commonly used for contraception, menstrual disorders, endometriosis, and hormone replacement therapy. It works as a synthetic form of progesterone that helps regulate the menstrual cycle, suppress ovulation, and balance hormonal activity in the body. Medroxyprogesterone Acetate belongs to a class of medications known as progestins and is widely used in women’s health and reproductive care. Find affordable Medroxyprogesterone Acetate options from trusted brands at DoctorOnCall.

Conclusion

Consult our doctors online for safe and effective use of Medroxyprogesterone Acetate tailored to your health needs. Find the best prices for affordable Medroxyprogesterone Acetate tablets and injections at DoctorOnCall Singapore.

Warnings

Kidney Safe If Prescribed

Dose adjustment of Medroxyprogesterone Acetate is not needed since it is eliminated by hepatic metabolism.

Alcohol Not Advisable

Alcohol will be an added risk of low bone mineral density with simultaneous use of Medroxyprogesterone Acetate. Taking Medroxyprogesterone Acetate with alcohol may alaso interfere with the absorption and metabolism of Medroxyprogesterone Acetate.

Pregnancy Not Safe - High Risk

Medroxyprogesterone Acetate is contraindicated to use during pregnancy. Both animals and human studies have proven adverse effects on the fetus. The risks clearly outweigh the benefits of Medroxyprogesterone Acetate. Please consult your doctor if pregnancy occurs.

Driving Generally Safe

Medroxyprogesterone Acetate usually does not affect the ability to drive. Do not drive unless you are feeling well.

Liver Safe If Prescribed

Medroxyprogesterone Acetate is contraindicated in patients with severe hepatic impairment. It should be used with caution in patients with any other liver disease. Dose adjustment of Medroxyprogesterone Acetate may be needed. Please consult your doctor.

Lactation Safe If Prescribed

Tablet: Medroxyprogesterone Acetate and its metabolites are can pass into breast milk but risk to baby is minimal. Please consult your doctor. Injection: No adverse effects have been noted to child exposed to Medroxyprogesterone Acetate, even though it can be secreted in breast milk.

Frequently Asked Questions

Written by

Dr. Adeline Carol Peters, Bachelor of Medicine and Bachelor of Surgery (MBBS) — Manipal Academy of Higher Education (MAHE)

Reviewed by

Dr. Mohd Izzat Amir Bin Awang, Doctor of Medicine (MD), University of Mansoura - Manchester