Memantine

Uses of Memantine

Memantine is commonly used in the treatment of Alzheimer's disease.

How Memantine Works

Memantine is a N-methyl-D-aspartate-receptor (NMDA receptor) antagonist which works by binding to NMDA-receptor and inhibits glutamate, an excitatory neurotransmitter in the CNS because in Alzheimer’s disease, Glutamate overstimulates glutamate receptors resulting in neuronal dysfunction.

Side Effects of Memantine

Headache, Somnolence, Dizziness, Constipation, Hypertension, Dyspnea, Abnormal gait, Hypertonia, Fungal infections, Cystitis, Thromboembolism, Increased libido, Psychotic reactions

Information About Memantine

Memantine is an NMDA receptor antagonist used to treat moderate to severe Alzheimer's disease in Singapore. Available as a 5mg–20mg oral tablet or extended-release capsule taken once daily, it is HSA-registered and available on prescription only in Singapore. Its unique mechanism — blocking pathological glutamate-mediated neuronal excitotoxicity while preserving physiological NMDA receptor activity — provides a complementary approach to acetylcholinesterase inhibitors, with combination therapy demonstrating additive cognitive benefits in moderate to severe Alzheimer's disease. A valid doctor's consultation is required before dispensing. Order Memantine online at DoctorOnCall Singapore with same-day delivery available. Speak to a DoctorOnCall physician today to check if Memantine is right for you.


Memantine is a medication commonly used to manage moderate to severe Alzheimer’s disease by helping support memory, thinking, and daily functioning. It works by regulating the activity of glutamate, a neurotransmitter involved in learning and memory, helping protect brain cells from excessive stimulation. Memantine belongs to a class of medications known as NMDA receptor antagonists and is widely used in neurological and dementia care. Find affordable Memantine options from trusted brands at DoctorOnCall.

Conclusion

Consult our doctors online for safe and effective use of Memantine tailored to your health needs. Find the best prices for affordable Memantine tablets, oral solutions, and extended-release capsules at DoctorOnCall Singapore.


Warnings

Kidney High Risk

Dose adjustment for Memantine may be needed in patients with moderate-to-severe kidney impairment. Please consult your doctor.

Alcohol Not Advisable

There is no data showed the interaction of Memantine with alcohol, however, it is not advisable to take both of them at the same time based on the fact that alcohol will double the side effects if Memantine such as dizziness, headache, nausea, vomiting and confusion.

Pregnancy Maybe Safe

Neither animal or human studies have shown adverse effect of Memantine on the fetus in the first trimester, as well as in later trimester. Limited studies done on pregnant women because of the usage of Memantine in treating Alzheimer's disease, which is commonly found in older age. Please consult your doctor before usage.

Driving Not advisable

Alzheimer's disease itself impairs your ability to drive alone and with the addition of Memantine, your driving impairment will be affected even more. Family members should receive prior warnings.

Liver Limited Data

Memantine should be used with caution in patients with mild to moderate liver disease but its use is not recommended in severe type. Please consult your doctor.

Lactation Limited Data

No data have found about lactation safety while consuming Memantine. However, the fact that Memantine has lipophilic character, it has to potential to be excreted in breast milk. Please stop breastfeeding if you are consuming Memantine.

Frequently Asked Questions

Written by

Dr. Adeline Carol Peters

, Bachelor of Medicine and Bachelor of Surgery (MBBS) — Manipal Academy of Higher Education (MAHE)

Reviewed by

Dr. Mohd Izzat Amir Bin Awang

, Doctor of Medicine (MD), University of Mansoura - Manchester