Nicotine

Uses of Nicotine

Nicotine is commonly used in the treatment of smoking addiction and helps in quitting smoking.

How Nicotine Works

Nicotine at low doses causes an initial stimulation of autonomic ganglia, adrenal medulla, neuromuscular junction, and brain. High doses of nicotine will produce initial ganglionic stimulation followed by inhibition of neurotransmission, and subsequently persistent depression of receptor activity.

Side Effects of Nicotine

Abdominal pain, Diarrhea, Nausea, Vomiting, Dizziness, Headache, Palpitation, Anxiety, Irritability, Lacrimation, Salivation, Runny nose, Insomnia

Information About Nicotine

Nicotine is an autonomic ganglion stimulant used as nicotine replacement therapy to support smoking cessation in Singapore. Available as a 2mg–4mg oral gum, lozenge, transdermal patch (7mg–21mg/24h), or nasal spray, it is HSA-registered and available on prescription only in Singapore. Nicotine replacement therapy reduces withdrawal symptoms and cravings during cessation attempts — combining a long-acting patch with a short-acting oral form for breakthrough cravings demonstrates superior quit rates compared to single-product NRT. A valid doctor's consultation is required before dispensing. Order Nicotine online at DoctorOnCall Singapore with same-day delivery available. Speak to a DoctorOnCall physician today to check if Nicotine is right for you.


Nicotine is a medication commonly used to support smoking cessation by helping reduce nicotine cravings and withdrawal symptoms in people who are trying to quit smoking. It works by providing controlled amounts of nicotine without the harmful chemicals found in tobacco smoke, helping ease the transition away from cigarettes and other tobacco products. Nicotine belongs to a class of medications known as nicotine replacement therapies and is widely used in smoking cessation and tobacco dependence management. Find affordable Nicotine options from trusted brands at DoctorOnCall.

Conclusion

Consult our doctors online for safe and effective use of Nicotine tailored to your health needs. Find the best prices for affordable Nicotine patches, gums, lozenges, inhalers, and oral sprays at DoctorOnCall Singapore.


Warnings

Kidney Use With Care

Nicotine should be used with caution in patients with severe renal impairment as the clearance of Nicotine or its metabolites may be decreased and therefore, there is an increased risk of side effects.

Alcohol Safe

It is safe to consume alcohol while on Nicotine. However, the combination of both may cause an increase in dopamine release which is responsible to cause euphoria.

Pregnancy Not Safe

It is recommended that pregnant women should stop smoking without requiring Nicotine replacement therapy. Human studies have reported that there is a risk to the fetus, but potential benefits may allow the usage of Nicotine in pregnancy. This is because the fetus's risk could be lower than the risk caused by cigarette smoking as there is lower maximal plasma Nicotine concentration. In the third trimester, Nicotine can cause changes in fetal heart rate and this could affect the fetus close to delivery.

Driving Generally Safe

Nicotine usually does not affect the ability to drive. Do not drive unless you are feeling well.

Liver Limited Data

Nicotine should be used with caution in patients with moderate to severe liver impairment as the clearance of Nicotine or its metabolites may be decreased. As a result, there is an increased risk of side effects.

Lactation Limited Data

Nicotine can be found in the breast milk of mothers on treatment therefore, it should be avoided during breastfeeding. There is limited data on the usage of Nicotine while breastfeeding. If Nicotine replacement therapy is essential, it should be taken just after breastfeeding and not two hours before breastfeeding.

Written by

Dr. Adeline Carol Peters

, Bachelor of Medicine and Bachelor of Surgery (MBBS) — Manipal Academy of Higher Education (MAHE)

Reviewed by

Dr. Mohd Izzat Amir Bin Awang

, Doctor of Medicine (MD), University of Mansoura - Manchester