Paliperidone

Uses of Paliperidone

Paliperidone is commonly used to treat schizophrenia and schizoaffective disorder in the adolescent and adults.

How Paliperidone Works

Paliperidone is an atypical antipsychotic which inhibits dopamine D2, serotonin (5-HT2A), adrenergic (α1 and α2), and histamine (H1) receptors. It also causes less catalepsy and motor functions than traditional neuroleptics. It also causes less extrapyramidal side effects.

Side Effects of Paliperidone

Headache, Insomnia, Sedation/somnolence, Parkinsonism, Akathisia, Increased heart rate, Tremor, Dystonia, Upper respiratory tract infection, Anxiety, Dizziness, Weight increased, Nausea, Agitation, Constipation, Vomiting, Fatigue, Depression, Dyspepsia, Diarrhea, Dry mouth, Toothache, Musculoskeletal pain, Increased blood pressure, Back pain, Cough.

Information About Paliperidone

Paliperidone is an atypical antipsychotic used to treat schizophrenia and schizoaffective disorder in Singapore. Available as a 3mg–12mg extended-release oral tablet taken once daily or as a monthly or three-monthly long-acting injectable formulation, it is HSA-registered and available on prescription only in Singapore. As the active metabolite of risperidone, paliperidone provides equivalent antipsychotic efficacy with more predictable pharmacokinetics across CYP2D6 metaboliser phenotypes — its long-acting injection formulations significantly improve medication adherence in patients with compliance difficulties. A valid doctor's consultation is required before dispensing. Order Paliperidone online at DoctorOnCall Singapore with same-day delivery available. Speak to a DoctorOnCall physician today to check if Paliperidone is right for you.


Paliperidone is a medication commonly used to treat schizophrenia and schizoaffective disorder by helping regulate the activity of neurotransmitters in the brain. It works by affecting dopamine and serotonin receptors, which can help improve symptoms such as hallucinations, delusions, disorganised thinking, and mood disturbances. Paliperidone belongs to a class of medications known as atypical antipsychotics and is widely used in mental health care. Find affordable Paliperidone options from trusted brands at DoctorOnCall.

Conclusion

Consult our doctors online for safe and effective use of Paliperidone tailored to your health needs. Find the best prices for affordable Paliperidone tablets, extended-release tablets, and long-acting injectable formulations at DoctorOnCall Singapore.


Warnings

Kidney Use With Care

Paliperidone should be used with caution in patients with kidney disease. Dose adjustment of Paliperidone may be needed. Please consult your doctor before using it. Use of Paliperidone is not recommended in patients with end-stage kidney failure.

Alcohol Not Advisable

Consuming alcohol can potentiate the effects of CNS depressant caused by Paliperidone. Please consult your doctor before using it.

Pregnancy Not Safe

Paliperidone may be unsafe to use during pregnancy. There are limited animal and human studies to show adverse effects on the pregnancy. The benefits from use in pregnant women may be acceptable despite the risk. Please consult your doctor before using it.

Driving Not advisable

Consuming alcohol can potentiate the effects of CNS depressant caused by Paliperidone which could affect your ability to concentrate and drive. Do not drive unless you are feeling well.

Liver Use With Care

Paliperidone should be used with caution in patients with liver disease. Dose adjustment of Paliperidone may be needed. Please consult your doctor before using it.

Lactation Not Advisable

Paliperidone is excreted into human breast milk. Studies suggest that there is potential adverse effect on feeding baby. Paliperidone is not recommended for use in pregnant women.

Frequently Asked Questions

Written by

Dr. Adeline Carol Peters

, Bachelor of Medicine and Bachelor of Surgery (MBBS) — Manipal Academy of Higher Education (MAHE)

Reviewed by

Dr. Mohd Izzat Amir Bin Awang

, Doctor of Medicine (MD), University of Mansoura - Manchester