Paricalcitol

Uses of Paricalcitol

Paricalcitol is commonly used to treat and prevent secondary hyperparathyroidism due to chronic kidney disease.

How Paricalcitol Works

Paricalcitol is a synthetic vit D analogue of calcitriol which activates vitamin D receptors in the kidneys, bones and intestine as well as the calcium sensing receptor in parathyroid gland. The PTH levels is reduced by inhibiting PTH synthesis and secretion, and improves calcium and phosphate level in metabolic bone disease.

Side Effects of Paricalcitol

Hypercalcaemia, hypercalciuria and hyperphosphatemia, Dizziness, Palpitations, Dyspepsia, Taste disturbance, Dry mouth, Nausea, Vomiting, Constipation, Diarrhea, Abdominal discomfort, Increased blood creatinine, Breast tenderness, Hypoparathyroidism, Musculoskeletal pain, Rash, Malaise, Pyrexia.

Information About Paricalcitol

Paricalcitol is a selective vitamin D receptor activator used to prevent and treat secondary hyperparathyroidism in chronic kidney disease in Singapore. Available as a 1mcg–2mcg oral capsule taken three times weekly or as an intravenous injection for haemodialysis patients, it is HSA-registered and available on prescription only in Singapore. Compared to calcitriol, paricalcitol selectively activates parathyroid vitamin D receptors with less effect on intestinal calcium and phosphate absorption, reducing the risk of hypercalcaemia and hyperphosphataemia in renal patients. A valid doctor's consultation is required before dispensing. Order Paricalcitol online at DoctorOnCall Singapore with same-day delivery available. Speak to a DoctorOnCall physician today to check if Paricalcitol is right for you.

Paricalcitol is a medication commonly used to prevent and treat secondary hyperparathyroidism in patients with chronic kidney disease. It works as a synthetic vitamin D analogue that helps regulate parathyroid hormone (PTH) levels, calcium balance, and bone metabolism. Paricalcitol belongs to a class of medications known as vitamin D receptor activators and is widely used in renal and endocrine care. Find affordable Paricalcitol options from trusted brands at DoctorOnCall.

Conclusion

Consult our doctors online for safe and effective use of Paricalcitol tailored to your health needs. Find the best prices for affordable Paricalcitol capsules and injections at DoctorOnCall Singapore.

Warnings

Kidney Use With Care

Paricalcitol should be used with caution in patients with mild to moderate kidney disease. Dose adjustment of Paricalcitol may be needed. Please consult your doctor before using it. Use of Paricalcitol in patients with severe kidney disease is unknown.

Alcohol Not Advisable

It is unsafe to consume alcohol with Paricalcitol especially in individuals with alcoholism. Please consult your doctor before using it.

Pregnancy Not Safe

Paricalcitol may be unsafe to use during pregnancy. Animal studies have shown adverse effects on the fetus, however, there are limited human studies. The benefits from use in pregnant women may be acceptable despite the risk. Please consult your doctor before using it.

Driving Generally Safe

Paricalcitol cause minimal to no side effects which could affect your ability to concentrate and drive

Liver Limited Data

Paricalcitol should be used with caution in patients with mild to moderate liver disease. Dose adjustment of Paricalcitol is not needed. Please consult your doctor before using it. Use of Paricalcitol in patients with severe kidney disease is unknown.

Lactation Limited Data

Paricalcitol is excreted into breast milk of mammals but the excretion into human breast milk and its adverse effect on the feeding baby is inconclusive. The decision to discontinue breastfeeding or withhold medication is to be made after consulting your doctor.

Written by

Dr. Adeline Carol Peters, Bachelor of Medicine and Bachelor of Surgery (MBBS) — Manipal Academy of Higher Education (MAHE)

Reviewed by

Dr. Mohd Izzat Amir Bin Awang, Doctor of Medicine (MD), University of Mansoura - Manchester