Pazopanib

Uses of Pazopanib

Pazopanib is commonly used to treat renal cell carcinoma and Soft Tissue Sarcoma

How Pazopanib Works

Pazopanib is an inhibitor of receptor tyrosine kinases (RTKs) which are involved in the pathway of malignant cells proliferation resulting in the retardation of tumour growth. RTKs involved in the blockade include receptors for vascular endothelial growth factors, platelet-derived growth factors, and stem cell factor.

Side Effects of Pazopanib

Diarrhea, Hair colour change, Skin hypopigmentation, Exfoliative rash, Increased blood pressure, Nausea, Headache, Fatigue, Loss of appetite, Vomiting, Distortion of the sense of taste, Stomatitis, Weight decreased, Elevated liver enzymes

Information About Pazopanib

Pazopanib is a multi-targeted tyrosine kinase inhibitor used to treat advanced renal cell carcinoma and soft tissue sarcoma in Singapore. Available as a 200mg–800mg oral tablet taken once daily on an empty stomach at least one hour before or two hours after food, it is HSA-registered and available on prescription only in Singapore. Hepatotoxicity is a serious adverse effect requiring liver function monitoring at weeks 3, 5, 7, and 9, then monthly — severe ALT elevations necessitate dose reduction or permanent discontinuation based on the degree of liver enzyme elevation. A valid doctor's consultation is required before dispensing. Order Pazopanib online at DoctorOnCall Singapore with same-day delivery available. Speak to a DoctorOnCall physician today to check if Pazopanib is right for you.

Pazopanib is a medication commonly used to treat certain types of cancer, including advanced renal cell carcinoma and soft tissue sarcoma, by helping slow the growth and spread of cancer cells. It works by inhibiting multiple tyrosine kinase receptors involved in tumour growth and blood vessel formation. Pazopanib belongs to a class of medications known as tyrosine kinase inhibitors (TKIs) and is widely used in targeted cancer therapy and oncology care. Find affordable Pazopanib options from trusted brands at DoctorOnCall.

Conclusion

Consult our doctors online for safe and effective use of Pazopanib tailored to your health needs. Find the best prices for affordable Pazopanib tablets at DoctorOnCall Singapore.

Warnings

Kidney Use With Care

Pazopanib should be used with caution in patients with mild kidney disease. Dose adjustment of Pazopanib is not needed. Please consult your doctor before using it. Use of Pazopanib in patients with moderate to severe kidney disease is unknown.

Alcohol Limited Data

Certain food and medications will have interactions with concurrent use of Pazopanib but there is no specific data stating so. Please consult your doctor before using it.

Pregnancy Not Safe

Human studies have shown adverse effects on the fetus. However, the benefits from use in pregnant women may be acceptable despite the risk. Please consult your doctor before using it.

Driving Generally Safe

Pazopanib cause negligible to no side effects which could affect your ability to concentrate and drive. Do not drive unless you are feeling well.

Liver Limited Data

Pazopanib should be used with caution in patients with mild to moderate liver disease. Dose adjustment of Pazopanib may be needed. Please consult your doctor before using it. Use of Pazopanib is not recommended in patients with severe kidney disease.

Lactation Limited Data

It is unknown whether Pazopanib is excreted into human breast milk and its potential adverse effect on the feeding baby. Please consult your doctor before using it.

Written by

Dr. Adeline Carol Peters, Bachelor of Medicine and Bachelor of Surgery (MBBS) — Manipal Academy of Higher Education (MAHE)

Reviewed by

Dr. Mohd Izzat Amir Bin Awang, Doctor of Medicine (MD), University of Mansoura - Manchester