Prilocaine

Uses of Prilocaine

Prilocaine is commonly used to numb tissues in a specific area, local Anesthesia, intravenous regional anesthesia, spinal or epidural anesthesia, perpheral nerve block.

How Prilocaine Works

Prilocaine is a local anaesthetic. It prevents conduction of nerve impulses that provide perception of pain, cold, heat, pressure and touch by selectively binds to the intracellular surface of Na channels and reversibly inhibits influx of Na along nerve fibres.

Side Effects of Prilocaine

Paraesthesia, Dizziness, Low heart rate, High/ low blood pressure, Nausea and vomiting

Information About Prilocaine

Prilocaine is an amide local anaesthetic used for dental anaesthesia, regional nerve blocks, and topical anaesthesia in combination with lidocaine in Singapore. Available as a dental cartridge injection or as a 2.5% component of EMLA cream applied topically, it is HSA-registered and available on prescription only in Singapore. High doses of prilocaine carry a specific risk of methaemoglobinaemia due to accumulation of its metabolite o-toluidine — this is particularly relevant in neonates and during intravenous regional anaesthesia where larger doses are used. A valid doctor's consultation is required before dispensing. Order Prilocaine online at DoctorOnCall Singapore with same-day delivery available. Speak to a DoctorOnCall physician today to check if Prilocaine is right for you.


Prilocaine is a medication commonly used to provide local anaesthesia during minor medical, dental, and surgical procedures. It works by blocking nerve signals in the area where it is applied or injected, helping prevent the sensation of pain. Prilocaine belongs to a class of medications known as local anaesthetics and is widely used in procedural and pain management care. Find affordable Prilocaine options from trusted brands at DoctorOnCall.

Conclusion

Consult our doctors online for safe and effective use of Prilocaine tailored to your health needs. Find the best prices for affordable Prilocaine injections, creams, and topical anaesthetic formulations at DoctorOnCall Singapore.


Warnings

Kidney Use With Care

Dose adjustment of Prilocaine may be needed in patients with kidney disease especially if it is administered intrathecally. Please consult your doctor.

Alcohol Safe

There is no information regarding drug interactions Prilocaine with Alcohol.

Pregnancy Maybe Safe

Prilocaine may be unsafe to use in pregnancy. Animal studies do not indicate any reproductive toxicity to the fetus. Nevertheless, due to high concentrations of anesthetic reaching the foetus, adverse effects such as foetal bradycardia, seem to be most apparent in paracervical block anaesthesia.

Driving Not advisable

Do not drive unless you are feeling well. Prilocaine may cause side effects such as dizziness, labile blood pressure and palpitations, all of which could affect the ability to concentrate and drive.

Liver Use With Care

In patients with liver disease, Prilocaine should be used with caution. Dose titration of Prilocaine may be necessary if it is administered intrathecally. Please consult your doctor.

Lactation Not Advisable

Prilocaine enters human breast milk. Therefore special precautions must be taken if Prilocaine must be used during lactation. Please discuss with your doctor.

Frequently Asked Questions

Written by

Dr. Adeline Carol Peters

, Bachelor of Medicine and Bachelor of Surgery (MBBS) — Manipal Academy of Higher Education (MAHE)

Reviewed by

Dr. Mohd Izzat Amir Bin Awang

, Doctor of Medicine (MD), University of Mansoura - Manchester