Probenecid

Uses of Probenecid

Probenecid is commonly used in the treatment of Gout

How Probenecid Works

Probenecid is a medication to increase uric acid excretion. Probenecid works by inhibiting competitively the reabsorption of uric acid at the proximal convoluted tubules of the kidney causing an increase in excretion of uric acid & reduction in serum uric acid level concomitantly.

Side Effects of Probenecid

Nausea, vomiting, anorexia, headache, sore gums, flushing, alopecia, dizziness, anaemia, urinary frequency, hypersensitivity

Information About Probenecid

Probenecid is a uricosuric agent used to treat chronic hyperuricaemia and gout, and as a penicillin potentiator in certain antibiotic regimens in Singapore. Available as a 250mg–500mg oral tablet taken twice daily with a meal, it is HSA-registered and available on prescription only in Singapore. High fluid intake of at least two litres daily is mandatory throughout therapy to prevent uric acid crystal deposition in the urinary tract — probenecid should not be initiated during acute gout flares as it can prolong and worsen acute attacks. A valid doctor's consultation is required before dispensing. Order Probenecid online at DoctorOnCall Singapore with same-day delivery available. Speak to a DoctorOnCall physician today to check if Probenecid is right for you.

Probenecid is a medication commonly used to treat gout and hyperuricaemia by helping lower uric acid levels in the blood. It works by increasing the excretion of uric acid through the kidneys, reducing the risk of uric acid crystal formation in the joints. Probenecid belongs to a class of medications known as uricosuric agents and is widely used in rheumatology and gout management. Find affordable Probenecid options from trusted brands at DoctorOnCall.

Conclusion

Consult our doctors online for safe and effective use of Probenecid tailored to your health needs. Find the best prices for affordable Probenecid tablets at DoctorOnCall Singapore.

Warnings

Kidney Use With Care

When you first begin taking Probenecid, the amount of uric acid in the kidneys is greatly increased. This may cause kidney stones or other kidney problems in some people. The presence of other medical problems may affect the use of this medicine. Make sure you tell your doctor of existing kidney disease.

Alcohol Not Advisable

Drinking too much alcohol may increase the amount of uric acid in the blood and lessen the effects of this medicine.

Pregnancy Maybe Safe

Probenecid crosses the placenta barrier and appears in cord blood. The use of any drug in women of child bearing potential requires that the anticipated benefit be weighed against possible hazards.

Driving Generally Safe

Probenecid usually does not affect the ability to drive. Do not drive unless you are feeling well.

Liver Limited Data

There are no reports on the frequency of liver test abnormalities during Probenecid therapy, but they are probably rare as Probenecid is largely secreted unchanged in the urine.

Lactation Limited Data

There are no adequate studies in women for determining infant risk when using this medication during breastfeeding. Weigh the potential benefits against the potential risks before taking this medication while breastfeeding.

Written by

Dr. Adeline Carol Peters, Bachelor of Medicine and Bachelor of Surgery (MBBS) — Manipal Academy of Higher Education (MAHE)

Reviewed by

Dr. Mohd Izzat Amir Bin Awang, Doctor of Medicine (MD), University of Mansoura - Manchester