Proguanil

Uses of Proguanil

Proguanil is commonly used to treat Cerebral Malaria, Malaria, prevention of Malaria

How Proguanil Works

Proguanil is an antimalarial agent. It prevents nucleic acid synthesis in the parasite by inhibiting enzyme, plasmodial dihydrofolate reductase.

Side Effects of Proguanil

Mild gastric intolerance Diarrhea Constipation aphthous ulceration Urticaria Angioedema Reversible hair loss

Information About Proguanil

Proguanil is an antifolate antimalarial used for malaria prophylaxis — typically in combination with chloroquine or atovaquone — in Singapore. Available as a 100mg oral tablet taken once daily starting one week before travel and continuing four weeks after return, it is HSA-registered and available on prescription only in Singapore. It must be taken at the same time each day with food or milk — irregular dosing substantially reduces its prophylactic efficacy as proguanil requires consistent plasma levels to maintain adequate antifolate activity in malaria-endemic regions. A valid doctor's consultation is required before dispensing. Order Proguanil online at DoctorOnCall Singapore with same-day delivery available. Speak to a DoctorOnCall physician today to check if Proguanil is right for you.


Proguanil is an antimalarial medication commonly used to prevent and treat malaria, particularly when used in combination with other antimalarial agents. It works by interfering with the growth and reproduction of Plasmodium parasites, helping prevent the development and spread of malaria infection. Proguanil belongs to a class of medications known as antimalarial agents and is widely used in infectious disease and travel medicine care. Find affordable Proguanil options from trusted brands at DoctorOnCall.

Conclusion

Consult our doctors online for safe and effective use of Proguanil tailored to your health needs. Find the best prices for affordable Proguanil tablets and combination antimalarial formulations at DoctorOnCall Singapore.


Warnings

Kidney Use With Care

Proguanil should be used with caution in patients with kidney disease. Dose titration of Proguanil according to clinical status may be needed. Please consult your doctor.

Alcohol Safe

It is safe to consume alcohol with Proguanil as there is no known drug interaction.

Pregnancy Limited Data

There are limited human studies of the use of Proguanil in pregnancy. It should not be used in pregnancy unless the benefits from use in pregnant women outweigh the risks. Please consult your doctor.

Driving Generally Safe

Do not drive unless you are feeling well. There is no evidence that Proguanil may affect the ability to drive and general concentration.

Liver Safe If Prescribed

There is no information regarding the safety of Proguanil in patient with liver disease.

Lactation Safe If Prescribed

Proguanil is found to be excreted in human breast milk. However, the amount is negligible.

Frequently Asked Questions

Written by

Dr. Adeline Carol Peters

, Bachelor of Medicine and Bachelor of Surgery (MBBS) — Manipal Academy of Higher Education (MAHE)

Reviewed by

Dr. Mohd Izzat Amir Bin Awang

, Doctor of Medicine (MD), University of Mansoura - Manchester