Promethazine

Uses of Promethazine

Promethazine is commonly used in the treatment of motion sickness, vertigo, hay fever, urticaria, pruritis, angioedema, rhinitis, conjunctivitis and insomnia.

How Promethazine Works

Promethazine works by inhibiting the postsynaptic mesolimbic dopaminergic receptors in the brain which produces the α-adrenergic blocking effect and suppresses the release of hypothalamic and hypophyseal hormones. Antiemetic activity will be produced through muscarinic blocking and also it competes with histamine to bind with H1-receptor

Side Effects of Promethazine

Bradycardia, Tachycardia, Hypotension, Jaundice, Neuroleptic Malignant Syndrome (NMS)

Information About Promethazine

Promethazine is a first-generation phenothiazine antihistamine used to treat allergic conditions, motion sickness, nausea, and insomnia in Singapore. Available as a 10mg–25mg oral tablet taken two to four times daily or as an intramuscular injection for severe nausea, it is HSA-registered and available on prescription only in Singapore. Promethazine is contraindicated in children under two years of age due to risk of fatal respiratory depression — even in older children, it must be used at the lowest effective dose for the shortest duration. A valid doctor's consultation is required before dispensing. Order Promethazine online at DoctorOnCall Singapore with same-day delivery available. Speak to a DoctorOnCall physician today to check if Promethazine is right for you.


Promethazine is a medication commonly used to relieve allergy symptoms, nausea, vomiting, motion sickness, and short-term sleep disturbances. It works by blocking the action of histamine and certain signals in the brain that trigger allergic reactions, nausea, and vomiting. Promethazine belongs to a class of medications known as first-generation antihistamines and antiemetic agents and is widely used in allergy, respiratory, and gastrointestinal care. Find affordable Promethazine options from trusted brands at DoctorOnCall.

Conclusion

Consult our doctors online for safe and effective use of Promethazine tailored to your health needs. Find the best prices for affordable Promethazine tablets, syrups, suppositories, and injections at DoctorOnCall Singapore.


Warnings

Kidney Use With Care

Promethazine should be used with caution in patients with kidney impairment. Dose adjustment of Promethazine may be needed. Please consult your doctor.

Alcohol Not Advisable

It is not advisable to drink alcohol with Promethazine as it enhances the CNS effects of the Alcohol.

Pregnancy Not Safe

Promethazine may be unsafe to use during pregnancy. Animal studies have shown side effects on the fetus, however, there are limited human studies. The benefits from use in pregnant women may be acceptable despite the risk. Please consult your doctor.

Driving Not advisable

Do not drive unless you are feeling well. Promethazine may cause side effects such as marked drowsiness which could affect the ability to concentrate and drive.

Liver Use With Care

Promethazine should be used with caution in patients with liver disorder. Dose adjustment of Promethazine may be needed. Please consult your doctor.

Lactation Not Advisable

Promethazine is shown to be excreted in breast milk. It is not advisable for women to breastfeed while consuming Promethazine because of its potential adverse drug effects on infants.

Frequently Asked Questions