Propylthiouracil

Uses of Propylthiouracil

Propylthiouracil is commonly used to treat Hyperthyroidism

How Propylthiouracil Works

Propylthiouracil is able to bind to thyroid peroxidase which will lead to the prevention of iodide to iodine and incorporation of iodides to thyroglobulin. This mechanism will reduce the production of new thyroid hormones in patients with hyperthyroidism.

Side Effects of Propylthiouracil

Decreased white blood cells/platelets, Lupus-like syndrome, Cutaneous vasculitis, Skin rash, Joint pain, Fever, Gut disturbances, Headache, Agranulocytosis, Aplastic anaemia, Liver dysfunction

Information About Propylthiouracil

Propylthiouracil is an antithyroid agent used to treat hyperthyroidism and thyroid storm, and is preferred over carbimazole in the first trimester of pregnancy in Singapore. Available as a 50mg–200mg oral tablet taken two to four times daily, it is HSA-registered and available on prescription only in Singapore. Liver function monitoring is essential during therapy as propylthiouracil carries a risk of severe drug-induced hepatotoxicity including fulminant hepatic failure — patients should report any jaundice, dark urine, or abdominal pain immediately. A valid doctor's consultation is required before dispensing. Order Propylthiouracil online at DoctorOnCall Singapore with same-day delivery available. Speak to a DoctorOnCall physician today to check if Propylthiouracil is right for you.


Propylthiouracil is a medication commonly used to treat hyperthyroidism and other conditions associated with an overactive thyroid gland. It works by reducing the production of thyroid hormones and inhibiting the conversion of thyroxine (T4) to the more active triiodothyronine (T3), helping restore normal thyroid function. Propylthiouracil belongs to a class of medications known as antithyroid agents and is widely used in endocrine care. Find affordable Propylthiouracil options from trusted brands at DoctorOnCall.

Conclusion

Consult our doctors online for safe and effective use of Propylthiouracil tailored to your health needs. Find the best prices for affordable Propylthiouracil tablets at DoctorOnCall Singapore.


Warnings

Kidney Use With Care

Dose adjustment is needed in patients with kidney impairment. Please consult your doctor.

Alcohol Not Advisable

Alcohol may further damage the liver which is caused by Propylthiouracil. Thus, it is not advisable to consume alcohol and Propylthiouracil concomitantly.

Pregnancy Not Safe

Animal studies and human studies have shown reproductive toxicities. Thus, Propylthiouracil is contraindicated during pregnancy.

Driving Generally Safe

There are no studies on the effect of Propylthiouracil on the ability to drive. Do not drive unless you are feeling well.

Liver Use With Care

Dose adjustment is needed in patients with liver impairment. Please consult your doctor.

Lactation Not Advisable

Excretion of Propylthiouracil has been found in human breast milk. Thus, it is contraindicated during breastfeeding.

Frequently Asked Questions

Written by

Dr. Adeline Carol Peters

, Bachelor of Medicine and Bachelor of Surgery (MBBS) — Manipal Academy of Higher Education (MAHE)

Reviewed by

Dr. Mohd Izzat Amir Bin Awang

, Doctor of Medicine (MD), University of Mansoura - Manchester