Prucalopride

Uses of Prucalopride

Prucalopride is commonly used to chronic idiopathic constipation.

How Prucalopride Works

Prucalopride's exerts its effect by binding to selective 5-HT4 receptor, stimulating intestinal secretions, peristaltic reflex, and gastrointestinal motility.

Side Effects of Prucalopride

Headache, Dizziness, Fatigue, Nausea and vomiting, Diarrhea, Abdominal pain, Dyspepsia, Flatulence, Decreased appetite

Information About Prucalopride

Prucalopride is a selective 5-HT4 receptor agonist used to treat chronic constipation unresponsive to conventional laxatives in Singapore. Available as a 1mg–2mg oral tablet taken once daily with or without food, it is HSA-registered and available on prescription only in Singapore. Its highly selective 5-HT4 agonism stimulates high-amplitude propagated contractions throughout the colon, restoring normal bowel motility without the cardiac arrhythmia risks associated with earlier non-selective 5-HT4 agonists such as cisapride. A valid doctor's consultation is required before dispensing. Order Prucalopride online at DoctorOnCall Singapore with same-day delivery available. Speak to a DoctorOnCall physician today to check if Prucalopride is right for you.


Prucalopride is a medication commonly used to treat chronic constipation in adults when other laxatives have not provided adequate relief. It works by stimulating serotonin (5-HT4) receptors in the gastrointestinal tract, helping increase bowel motility and promote regular bowel movements. Prucalopride belongs to a class of medications known as selective serotonin 5-HT4 receptor agonists and is widely used in gastrointestinal care. Find affordable Prucalopride options from trusted brands at DoctorOnCall.

Conclusion

Consult our doctors online for safe and effective use of Prucalopride tailored to your health needs. Find the best prices for affordable Prucalopride tablets at DoctorOnCall Singapore.


Warnings

Kidney Use With Care

Prucalopride should be used with caution in patients with severe kidney impairment. Dose adjustment of Prucalopride may be needed for patients with creatinine clearance less than 30 mL/min. Please consult your doctor.

Alcohol Safe

Prucalopride has no effect on the metabolism of alcohol.

Pregnancy Limited Data

Prucalopride is not recommended for the usage of women in the reproductive age who practice unprotected coitus.

Driving Not advisable

Do not drive unless you are feeling well. Prucalopride may cause side effects such as dizziness or tiredness, all of which could affect the ability to concentrate and drive.

Liver Limited Data

You may start Prucalopride with 1 mg once daily for patients with severe hepatic impairment (Child-Pugh class C) and may be increased to 2 mg if tolerated with Prucalopride. However, for patients with mild to moderate liver disease, no dose adjustment is needed.

Lactation Limited Data

Prucalopride is excreted into the breast milk and safe to use during lactation at therapeutic dose. Limited human data suggests that Prucalopride does not represent a significant risk to the baby. Please consult your doctor to be sure.

Frequently Asked Questions