Ranolazine

Uses of Ranolazine

Ranolazine is commonly used in the treatment of Angina Heart Related Chest Pain.

How Ranolazine Works

Ranolazine is an anti-anginal drug. It inhibits the late Na current and other cardiac ion channels and transporters. It reduces the magnitude of the late Na current resulting in reduction intracellular Na concentrations, reversal of Ca overload, restoration of ventricular pump function, and prevention of ischaemia-induced arrhythmias.

Side Effects of Ranolazine

Nausea and vomiting, Dizziness, Headache, Constipation, Palpitations, Vertigo, Visual disturbances, Tinnitus, Dry Mouth, Abdominal pain, Hypotension, Haematuria

Information About Ranolazine

Ranolazine is a late sodium current inhibitor used as adjunctive therapy for chronic stable angina in Singapore. Available as a 375mg–750mg extended-release oral tablet taken twice daily, it is HSA-registered and available on prescription only in Singapore. Unlike conventional antianginals, ranolazine reduces myocardial ischaemia without affecting heart rate or blood pressure through selective late sodium current inhibition — this unique mechanism allows it to be added to maximally tolerated antianginal therapy when symptoms persist. A valid doctor's consultation is required before dispensing. Order Ranolazine online at DoctorOnCall Singapore with same-day delivery available. Speak to a DoctorOnCall physician today to check if Ranolazine is right for you.


Ranolazine is a medication commonly used to treat chronic angina (chest pain) by helping improve blood flow efficiency in the heart. It works by affecting sodium channels in heart muscle cells, which helps reduce the heart’s oxygen demand and improve its ability to function under stress. Ranolazine belongs to a class of medications known as antianginal agents and is widely used in cardiovascular care. Find affordable Ranolazine options from trusted brands at DoctorOnCall.

Conclusion

Consult our doctors online for safe and effective use of Ranolazine tailored to your health needs. Find the best prices for affordable Ranolazine extended-release tablets at DoctorOnCall Singapore.


Warnings

Kidney High Risk

Ranolazine should be used with caution in patients with mild and moderate kidney disease. Dose adjustment of Ranolazine may be needed. However, for patients with creatinine clearance less than 30 mL/min, Ranolazine is contraindicated. Please consult your doctor.

Alcohol Not Advisable

It is unsafe to consume alcohol with Ranolazine because it may worsen the side effects of Ranolazine such as headache, dizziness, nausea, and palpitations.

Pregnancy Not Safe

Ranolazine may be unsafe to use during pregnancy. Animal studies have shown adverse reactions on the fetus, however, there are limited human studies. Hence, it is only used when clearly necessary. Please consult your doctor.

Driving Not advisable

There are no studies of Ranolazine on driving ability. However, it may cause some side effects which may affect driving ability. Do not drive when not feeling well.

Liver Limited Data

Ranolazine should be used with caution in patients with a history of liver disease. Dose adjustment of Ranolazine may be needed in mild liver impairment. However, Ranolazine is contraindicated for patients with moderate to severe hepatic impairment. Please consult your doctor.

Lactation Limited Data

No reports explaining the use of Ranolazine for breastfeeding mothers are available. Animal studies have shown the excretion of Ranolazine in milk. Therefore, it should not be used during breast-feeding as we may not know the side effects.

Frequently Asked Questions