Rifampicin

Uses of Rifampicin

Rifampicin is commonly used in the treatment of leprosy, Tuberculosis (TB), and tuberculosis with HIV infection

How Rifampicin Works

Rifampicin is an Anti-TB agent. Formation of chain for RNA synthesis in susceptible bacteria will be suppressed by Rifampicin. This happens by the binding to the β subunit of DNA-dependent RNA polymerase which leads to blocking of RNA transcription which in turn killing the bacteria.

Side Effects of Rifampicin

Facial flushing, Flu-like symptoms(Fever, Headache, Dizziness, Bone pain, Shortness of breath, Malaise), GI disturbance (Nausea, Vomiting, Diarrohea), Muscular weakness, Red discolouration of urine

Information About Rifampicin

Rifampicin is a broad-spectrum bactericidal antimycobacterial used as a cornerstone of tuberculosis, leprosy, and meningococcal prophylaxis treatment in Singapore. Available as a 150mg–600mg oral capsule taken once daily on an empty stomach, it is HSA-registered and available on prescription only in Singapore. Rifampicin is one of the most potent CYP450 enzyme inducers known — it reduces the plasma levels of numerous co-prescribed drugs including warfarin, oral contraceptives, antiretrovirals, and antifungals, requiring dose adjustments and contraceptive method changes. A valid doctor's consultation is required before dispensing. Order Rifampicin online at DoctorOnCall Singapore with same-day delivery available. Speak to a DoctorOnCall physician today to check if Rifampicin is right for you.


Rifampicin is an antibiotic medication commonly used to treat tuberculosis (TB), certain bacterial infections, and to prevent the spread of specific infections such as meningococcal disease. It works by inhibiting bacterial RNA synthesis, helping stop the growth and multiplication of susceptible bacteria. Rifampicin belongs to a class of medications known as rifamycin antibiotics and is widely used in infectious disease care. Find affordable Rifampicin options from trusted brands at DoctorOnCall.

Conclusion

Consult our doctors online for safe and effective use of Rifampicin tailored to your health needs. Find the best prices for affordable Rifampicin capsules, tablets, oral suspensions, and combination anti-tuberculosis formulations at DoctorOnCall Singapore.


Warnings

Kidney Use With Care

Rifampicin should be used with caution in patients with kidney impairment. Dose adjustment of Rifampicin may be needed. Please consult your doctor.

Alcohol Not Advisable

It is more likely to cause liver damage if the patient takes Rifampicin simultaneously with alcohol.

Pregnancy Not Safe

Rifampicin is known to cross the placental barrier and reach the foetus but there is no well-controlled studies in pregnant women, therefore, the effect is not known. Animal studies have shown teratogenic effects in very high dose. Usage may be unsafe and it should be used when only the benefits outweigh the risks.

Driving Generally Safe

There are no studies of Rifampicin on the ability to drive. Do not drive unless you are feeling well.

Liver Use With Care

Rifampicin is contraindicated in patients with jaundice. Dose adjustment of Rifampicin is necessary for patients with liver impairment. Please consult your doctor.

Lactation Not Advisable

Rifampicin is shown to be excreted in breast milk. It is not advisable for women to breastfeed while consuming Rifampicin because of its potential adverse drug effects on infants.

Frequently Asked Questions