Does roflumilast cause weight loss?

Yes, it does. However, the extent of weight loss was mostly seen in the first 4 weeks of treatment with roflumilast and was shown to occur in patients with greater fat mass. Patients were able to regain one-half of their weight lost in 3 months after discontinuing treatment with roflumilast.

Roflumilast

Uses of Roflumilast

Roflumilast is commonly used to treat Chronic Obstructive Pulmonary Disease (COPD)

How Roflumilast Works

Roflumilast is a phosphodiesterase-4 inhibitor which has anti-inflammatory and anti-modulatory effects in the lungs. Thus, it is able to help to improve the severity of COPD.

Side Effects of Roflumilast

Weight loss, Anxiety, Insomnia, Abdominal pain, Nausea, Diarrhea, Decreased appetite, Back pain, Headache, Dizziness

Information About Roflumilast

Roflumilast is a selective phosphodiesterase-4 inhibitor used to reduce COPD exacerbations in severe chronic bronchitis in Singapore. Available as a 250mcg–500mcg oral tablet taken once daily, it is HSA-registered and available on prescription only in Singapore. It is an add-on anti-inflammatory therapy — not a bronchodilator — indicated specifically for COPD patients with FEV1 below 50% predicted and chronic productive cough, where it reduces exacerbation frequency through cAMP-mediated reduction in airway inflammation. A valid doctor's consultation is required before dispensing. Order Roflumilast online at DoctorOnCall Singapore with same-day delivery available. Speak to a DoctorOnCall physician today to check if Roflumilast is right for you.

Roflumilast is a medication commonly used to reduce the risk of flare-ups in patients with severe chronic obstructive pulmonary disease (COPD) associated with chronic bronchitis. It works by inhibiting phosphodiesterase-4 (PDE4), helping reduce inflammation in the airways and improve respiratory health. Roflumilast belongs to a class of medications known as phosphodiesterase-4 inhibitors and is widely used in respiratory care. Find affordable Roflumilast options from trusted brands at DoctorOnCall.

Conclusion

Consult our doctors online for safe and effective use of Roflumilast tailored to your health needs. Find the best prices for affordable Roflumilast tablets at DoctorOnCall Singapore.

Warnings

Kidney Safe If Prescribed

Roflumilast is safe to be used in patients with kidney impairment.

Alcohol Not Advisable

There is no known interaction between alcohol and Roflumilast when consumed concomitantly. However, alcohol is not advisable for a patient with COPD as it will worsen the condition.

Pregnancy Not Safe

Animal studies have shown reproductive toxicities but there are limited data on the use of Roflumilast in pregnant women. Thus, it is not advisable to be used during pregnancy.

Driving Generally Safe

Roflumilast usually does not affect the ability to drive. Do not drive unless you are feeling well.

Liver Use With Care

Dose adjustment is needed in patients with mild liver impairment. Roflumilast is contraindicated in patients with moderate to severe liver impairment.

Lactation Not Advisable

Excretion of Roflumilast has been found in animal milk but it is unknown in human breast milk. Thus, it is not advisable to be used during breastfeeding as risks cannot be excluded.