Ruxolitinib

Uses of Ruxolitinib

Ruxolitinib is commonly used to treat Chronic Idiopathic Myelofibrosis and Polycythemia Vera.

How Ruxolitinib Works

Ruxolitinib is a selective Janus Associated Kinase (JAK) inhibitor which helps to mediate immune function and haematopoiesis. This is particularly helpful in patients with myelofibrosis and polycythemia vera which are characterized by abnormal JAK activity.

Side Effects of Ruxolitinib

Decreased in red blood cells/white blood cells/platelets, Increased risk of infections, Increased cholesterol and triglycerides level, Difficulty in breathing, Gut disturbances, Liver enzyme dysfunction, Weight gain, Oedema, Muscle spasm, Headache, Dizziness, Insomnia

Information About Ruxolitinib

Ruxolitinib is a JAK1/JAK2 inhibitor used to treat myelofibrosis, polycythaemia vera, and steroid-refractory graft-versus-host disease in Singapore. Available as a 5mg–25mg oral tablet taken twice daily, it is HSA-registered and available on prescription only in Singapore. Abrupt discontinuation can cause rapid return of splenomegaly and constitutional symptoms — doses should be tapered gradually and patients should not stop treatment without specialist guidance due to the risk of rebound disease acceleration. A valid doctor's consultation is required before dispensing. Order Ruxolitinib online at DoctorOnCall Singapore with same-day delivery available. Speak to a DoctorOnCall physician today to check if Ruxolitinib is right for you.

Ruxolitinib is a medication commonly used to treat certain blood disorders, including myelofibrosis, polycythaemia vera, and graft-versus-host disease. It works by inhibiting Janus kinase (JAK) enzymes, which are involved in signalling pathways that contribute to abnormal blood cell production and inflammation. Ruxolitinib belongs to a class of medications known as JAK inhibitors and is widely used in haematology and oncology care. Find affordable Ruxolitinib options from trusted brands at DoctorOnCall.

Conclusion

Consult our doctors online for safe and effective use of Ruxolitinib tailored to your health needs. Find the best prices for affordable Ruxolitinib tablets and topical formulations at DoctorOnCall Singapore.

Warnings

Kidney Use With Care

Dose adjustment is needed for patients with severe and end-stage kidney disease on dialysis. Please consult your doctor.

Alcohol Not Advisable

There is no known interaction between alcohol and Ruxolitinib when consumed concomitantly. However, it is not advisable to consume alcohol when receiving anticancer treatment.

Pregnancy Not Safe

Animal studies have shown reproductive toxicities but there are no human studies have been conducted. Thus, Ruxolitinib is contraindicated during pregnancy. Please consult your doctor.

Driving Generally Safe

Ruxolitinib usually does not affect the ability to drive. Do not drive unless you are feeling well.

Liver Use With Care

Dose adjustment is needed in patients with liver impairment. Please consult your doctor.

Lactation Not Advisable

Excretion of Ruxolitinib has been found in animal milk but it is unknown in human breast milk. Thus, it is not advisable to be used during breastfeeding as the risks cannot be excluded. Please consult your doctor.