Selegiline

Uses of Selegiline

Selegiline is commonly used to treat Parkinson's Disease

How Selegiline Works

Selegiline is a monoamine oxidase-B inhibitor which blocks the metabolism of dopamine in nigrostriatal pathways and increasing the dopaminergic activity. This is said to be the primary mechanism that helps to relieve symptoms in Parkinson’s disease.

Side Effects of Selegiline

Postural hypotension, Chest pain, Headache, Tremor, Vertigo, Dizziness, Mental disturbances, Gut disturbances, Difficulty in urination, Skin reactions, Joint/Muscle pain, Insomnia, Abnormal dreams, Liver enzyme dysfunction

Information About Selegiline

Selegiline is a selective irreversible MAO-B inhibitor used to treat Parkinson's disease as monotherapy or adjunct to levodopa in Singapore. Available as a 5mg oral tablet taken twice daily before noon or as a 1.25mg orally disintegrating tablet, it is HSA-registered and available on prescription only in Singapore. Selegiline and its metabolites include amphetamine derivatives — it must not be taken after noon as it causes insomnia from CNS stimulant properties, and concurrent use with pethidine carries a risk of life-threatening serotonergic reactions. A valid doctor's consultation is required before dispensing. Order Selegiline online at DoctorOnCall Singapore with same-day delivery available. Speak to a DoctorOnCall physician today to check if Selegiline is right for you.

Selegiline is a medication commonly used to treat Parkinson’s disease and, in certain formulations, depression. It works by inhibiting monoamine oxidase B (MAO-B), an enzyme responsible for breaking down dopamine in the brain, thereby helping increase dopamine levels and improve motor symptoms. Selegiline belongs to a class of medications known as MAO-B inhibitors and is widely used in neurology and mental health care. Find affordable Selegiline options from trusted brands at DoctorOnCall.

Conclusion

Consult our doctors online for safe and effective use of Selegiline tailored to your health needs. Find the best prices for affordable Selegiline tablets, capsules, orally disintegrating tablets, and transdermal patches at DoctorOnCall Singapore.

Warnings

Kidney Safe If Prescribed

Selegiline is safe to be used in patients with kidney impairment.

Alcohol Not Advisable

Alcohol may accentuate the sedative effect caused by Selegiline. Thus, it is not advisable to use alcohol and Selegiline concomitantly.

Pregnancy Not Safe

Animal studies have shown reproductive toxicities but there are limited data on the use of Selegiline during pregnancy as Parkinson's Disease usually occur after childbearing age. Thus, it is advisable to avoid Selegiline during pregnancy.

Driving Not advisable

Do not drive unless you are feeling well. Selegiline may cause side effects such as dizziness, headache, nausea or tiredness, all of which could affect your ability to concentrate and drive.

Liver Use With Care

Selegiline is safe to be used in patients with liver impairment.

Lactation Not Advisable

There are limited data on the use of Selegiline during breastfeeding. Thus, it is advisable to avoid Selegiline during breastfeeding.

Written by

Dr. Adeline Carol Peters, Bachelor of Medicine and Bachelor of Surgery (MBBS) — Manipal Academy of Higher Education (MAHE)

Reviewed by

Dr. Mohd Izzat Amir Bin Awang, Doctor of Medicine (MD), University of Mansoura - Manchester