Tegafur

Uses of Tegafur

Tegafur is commonly used to treat Cancer, Cancer Of Colon And Rectum and Stomach Cancer.

How Tegafur Works

Tegafur is an anticancer agent and it is the prodrug of fluorouracil. Fluorouracil is able to phosphorylate into its active metabolite (FdUMP) which inhibits the DNA synthesis and disrupts the RNA function of the cancer cells.

Side Effects of Tegafur

Nausea and vomiting, Anorexia, Hot flushes, Oedema, Skin itching, Neurotoxicity, Bone marrow suppression, Skin rash, Ocular irritation, Myocardial ischemia

Information About Tegafur

Tegafur is an oral fluoropyrimidine prodrug used as part of the S-1 combination (tegafur-gimeracil-oteracil) for gastric, colorectal, and lung cancer in Singapore. Available only as a fixed three-component combination taken twice daily with food per oncology protocol, it is HSA-registered and available on prescription only in Singapore. Tegafur is converted to fluorouracil intracellularly by CYP2A6 — patients with CYP2A6 poor metaboliser phenotypes may have reduced antitumour activity and require genotyping before initiation of S-1 regimens. A valid doctor's consultation is required before dispensing. Order Tegafur online at DoctorOnCall Singapore with same-day delivery available. Speak to a DoctorOnCall physician today to check if Tegafur is right for you.


Tegafur is a medication commonly used to treat certain types of cancer, including gastrointestinal cancers, as part of combination chemotherapy regimens. It works as a prodrug that is converted into fluorouracil (5-FU) in the body, helping interfere with cancer cell growth and replication. Tegafur belongs to a class of medications known as antimetabolite chemotherapy agents and is widely used in oncology care. Find affordable Tegafur options from trusted brands at DoctorOnCall.

Conclusion

Consult our doctors online for safe and effective use of Tegafur tailored to your health needs. Find the best prices for affordable Tegafur-containing capsules, tablets, and combination chemotherapy formulations at DoctorOnCall Singapore.


Warnings

Kidney Use With Care

Caution use of Tegafur has to be practised in patients with kidney impairment. Please consult your doctor.

Alcohol Not Advisable

Alcohol may decrease the metabolism of Tegafur when used concomitantly. Thus, it is not advisable to consume alcohol during cancer treatment with Tegafur.

Pregnancy Limited Data

There are no clinical data on the effect of Tegafur use in pregnant women. Thus, it is not advisable to be used during pregnancy. Please consult your doctor.

Driving Not advisable

Do not drive unless you are feeling well. Tegafur may cause side effects such as tiredness, blurred vision or nausea, all of which could affect your ability to concentrate and drive.

Liver Use With Care

Caution use of Tegafur has to be practised in patients with liver impairment. Please consult your doctor.

Lactation Not Advisable

Animal studies have shown the excretion of Tegafur in animal milk but it is unknown in human milk. Thus, it is not advisable to be used during breastfeeding. Please consult your doctor.