Ticlopidine

Uses of Ticlopidine

Ticlopidine is commonly used to treat certain condition such as Blood Clots, and used in the treatment of Heart Attack, and Unstable Angina

How Ticlopidine Works

Ticlopidine which is an antiplatelet drug act by inhibiting platelets from clumping together best known as platelet aggregation. It is used as a treatment in a condition such as blood clots thus helping the blood flow smoothly in your body.

Side Effects of Ticlopidine

Diarrhea, Nausea, Dyspepsia, Bleeding tendency, Rashes on skin, Increase in serum cholesterol level, Increase of Liver Function Tests

Information About Ticlopidine

Ticlopidine is a first-generation thienopyridine antiplatelet agent used to prevent thromboembolic stroke and cardiovascular events in Singapore. Available as a 250mg oral tablet taken twice daily with food, it is HSA-registered and available on prescription only in Singapore. Monthly full blood count monitoring during the first three months is mandatory as ticlopidine causes thrombotic thrombocytopenic purpura and neutropenia in a small but clinically significant proportion of patients — clopidogrel is now preferred over ticlopidine due to its superior safety profile. A valid doctor's consultation is required before dispensing. Order Ticlopidine online at DoctorOnCall Singapore with same-day delivery available. Speak to a DoctorOnCall physician today to check if Ticlopidine is right for you.

Warnings

Kidney Use With Care

There is limited study, however, the use of this drug will decrease its plasma clearance and increase bleeding time in a patient with renal impairment. Please consult your doctor before taking this medication.

Alcohol Not Advisable

Taking alcohol while you are on Ticlopidine may increase the chance of bleeding in your gastrointestinal tract (GIT)

Pregnancy Maybe Safe

Since there are no controlled data in human pregnancy for Ticlopidine and animal studies couldn't demonstrate a risk to the fetus, therefore this medication is advised to be given only when it benefits the pregnant lady

Driving Not advisable

Do not drive unless you are feeling well. Ticlopidine may cause side effects such as dizziness, headches or nausea, all of which could affect the ability to concentrate and drive.

Liver Limited Data

There is a limited study done for the use of Ticlopidine in patients suffering from the hepatic disease. However, since Ticlopidine is metabolized in the liver, the adjustment of the dosage has to be made by the doctors before initiating the therapy. The use of Ticlopidine is not recommended in patients with severe hepatic disease.

Lactation Limited Data

It is not known whether Ticlopidine is excreted in the breast milk of humans, however, it is excreted in the rat's milk upon research. The decision to continue or stop breastfeeding has to be made by the doctor. Please consult your doctor for further information.

Written by

Dr. Adeline Carol Peters, Bachelor of Medicine and Bachelor of Surgery (MBBS) — Manipal Academy of Higher Education (MAHE)

Reviewed by

Dr. Mohd Izzat Amir Bin Awang, Doctor of Medicine (MD), University of Mansoura - Manchester