Tofacitinib

Uses of Tofacitinib

Tofacitinib is commonly used to treat Psoriatic Arthritis, Rheumatoid Arthritis, Ulcerative Colitis

How Tofacitinib Works

Tofacitinib is a partial janus kinase (JAK) inhibitor that can reversibly inhibit the janus kinase-signal transducers and activators of transcription pathway which involves in haematopoiesis and immune cell function. Thus, it can help to reduce the inflammatory response in autoimmune diseases such as rheumatoid arthritis, psoriatic arthritis and ulcerative colitis.

Side Effects of Tofacitinib

Opportunistic infections, Anaemia, Headache, Hypertension, Cough, Abdominal pain, Nausea and vomiting, Diarrhea, Rash, Fever

Information About Tofacitinib

Tofacitinib is a JAK1/JAK3 inhibitor used to treat rheumatoid arthritis, psoriatic arthritis, ulcerative colitis, and ankylosing spondylitis in Singapore. Available as a 5mg–10mg oral tablet taken twice daily or as an 11mg extended-release tablet once daily, it is HSA-registered and available on prescription only in Singapore. Screening for latent tuberculosis, varicella zoster immunity, and hepatitis B is mandatory before initiation — thromboembolic events at higher doses have led to regulatory restrictions limiting 10mg twice daily use to patients without cardiovascular risk factors. A valid doctor's consultation is required before dispensing. Order Tofacitinib online at DoctorOnCall Singapore with same-day delivery available. Speak to a DoctorOnCall physician today to check if Tofacitinib is right for you.


Tofacitinib is a medication commonly used to treat autoimmune and inflammatory conditions such as rheumatoid arthritis, psoriatic arthritis, ulcerative colitis, and certain other immune-mediated disorders. It works by inhibiting Janus kinase (JAK) enzymes, helping reduce inflammation and abnormal immune system activity. Tofacitinib belongs to a class of medications known as JAK inhibitors and is widely used in rheumatology and gastroenterology care. Find affordable Tofacitinib options from trusted brands at DoctorOnCall.

Conclusion

Consult our doctors online for safe and effective use of Tofacitinib tailored to your health needs. Find the best prices for affordable Tofacitinib tablets, extended-release tablets, and oral solutions at DoctorOnCall Singapore.


Warnings

Kidney Use With Care

Dose adjustment is needed in patients with severe kidney impairment.

Alcohol Safe

There is no known interaction between alcohol and Tofacitinib when used concomitantly.

Pregnancy Not Safe

Animal studies have shown reproductive toxicities but there are limited data and well-controlled human studies on pregnant women. Thus, Tofacitinib is not advisable to be used during pregnancy. Please consult your doctor.

Driving Generally Safe

Tofacitinib usually does not affect the ability to drive. Do not drive unless you are feeling well.

Liver Use With Care

Dose adjustment is needed in patients with moderate kidney impairment. It is not advisable to be used in patients with severe liver impairment.

Lactation Not Advisable

Animal studies have shown the excretion of Tofacitinib in animal milk but it is unknown in human milk. Thus, Tofacitinib is not advisable to be used during breastfeeding. Please consult your doctor.

Frequently Asked Questions

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