Uracil

Uses of Uracil

Uracil is commonly in combination with Tegafur used to treat Breast Cancer, Cancer, Cancer Of Colon And Rectum, Cervical Cancer, Head And Neck Cancer, Lung Cancer, Pancreatic Cancer, Stomach Cancer, Urinary Bladder Cancer, Liver Cancer, Gallbladder Cancer and Bile Duct Cancer.

How Uracil Works

Uracil usually used in combination with Tegafur which is a prodrug of 5-fluorouracil. It helps to inhibit dihydropyrimidine dehydrogenase (DPD), the enzyme that metabolize 5-fluorouracil, thus increasing the activity of 5-fluorouracil to exert its anti-cancer property.

Side Effects of Uracil

Diarrhea, Dehydration, Gastrointestinal bleeding, Nausea, Vomiting, Abdominal pain, Tiredness, Jaundice, Decreased appetite, Loss of hair

Information About Uracil

Uracil is used as a component of the tegafur-uracil oral fluoropyrimidine combination for colorectal and other gastrointestinal cancers in Singapore. Available only within fixed-combination cancer treatment regimens taken with food per oncology protocol, it is HSA-registered and available on prescription only in Singapore. It inhibits dihydropyrimidine dehydrogenase-mediated fluorouracil catabolism, prolonging its antitumour activity — the combination provides sustained fluorouracil tumour tissue concentrations with a more manageable toxicity profile than continuous infusion regimens. A valid doctor's consultation is required before dispensing. Order Uracil online at DoctorOnCall Singapore with same-day delivery available. Speak to a DoctorOnCall physician today to check if Uracil is right for you.

Uracil is a medication component commonly used as part of combination chemotherapy regimens for the treatment of certain cancers, particularly gastrointestinal cancers. It works by enhancing and modulating the activity of fluoropyrimidine-based anticancer agents, helping improve their effectiveness against cancer cells. Uracil belongs to a class of medications known as antimetabolite chemotherapy modulators and is widely used in oncology care. Find affordable Uracil-containing treatment options from trusted brands at DoctorOnCall.

Conclusion

Consult our doctors online for safe and effective use of Uracil tailored to your health needs. Find the best prices for affordable Uracil-containing capsules, tablets, and combination chemotherapy formulations at DoctorOnCall Singapore.

Warnings

Kidney Use With Care

Caution use of Uracil related drug has to be practised in patients with kidney impairment.

Alcohol Not Advisable

It is unsafe to consume alcohol and Uracil simultaneously as alcohol will accentuate the side effects of Uracil such as drowsiness and headache. Please consult your doctor.

Pregnancy Not Safe - High Risk

Animal studies and human studies have shown reproductive toxicities to the foetus. Thus, Uracil related drug is not advisable to be used during pregnancy.

Driving Not advisable

Do not drive unless you are feeling well. Uracil related drug may cause side effects such as tiredness, nausea and vomiting, all of which could affect your ability to concentrate and drive.

Liver Use With Care

Caution use of Uracil related drug has to be practised in patients with liver impairment.

Lactation Not Advisable

Animal studies have shown the excretion of Uracil in the milk. Thus, Uracil is advisable not to be used during breastfeeding. If the usage is necessary, breastfeeding should be discontinued.

Written by

Dr. Adeline Carol Peters, Bachelor of Medicine and Bachelor of Surgery (MBBS) — Manipal Academy of Higher Education (MAHE)

Reviewed by

Dr. Mohd Izzat Amir Bin Awang, Doctor of Medicine (MD), University of Mansoura - Manchester