Can I take antacids, calcium, iron and magnesium supplements while on zoledronic acid?

You are advised to space the doses of zoledronic acid at least 60 minutes from your antacids, calcium, iron, aluminium and magnesium supplements as they can decrease the absorption of zoledronic acid into your body.

What can I do to keep my teeth healthy while on zoledronic acid?

You are encouraged to get a full dental assessment before you start your treatment with zoledronic acid and to go for a regular dental check up every 6 months. Besides that, you should also maintain good oral hygiene and avoid any invasive dental procedures while on zoledronic acid.

Why am I advised to take zoledronic acid with a full glass of water and not to lie down after taking zoledronic acid?

It is advised that you do not lie down for 30 minutes (60 minutes for after taking zoledronic acid to reduce the risk of zoledronic acid getting stuck in the lining of your throat and developing reflux.

Zoledronic Acid

Uses of Zoledronic Acid

Zoledronic acid is commonly used to treat Osteoporosis, Osteoporosis In Men, Post Menopausal Osteoporosis, Steroid Induced Osteoporosis

How Zoledronic Acid Works

Zoledronic acid is able to inhibit farnesyl pyrophosphate synthase in the osteoclasts leading to reduction of osteoclastic activity and rate of bone resorption, thus maintain a net gain in bone mass.

Side Effects of Zoledronic Acid

Bone/Joint/Muscle pain, Dizziness, Fever, Flu-like symptoms, Allergy reaction, Nausea, Vomiting, Diarrhea, Eye inflammation, Alopecia

Information About Zoledronic Acid

Zoledronic Acid is the most potent nitrogen-containing bisphosphonate used to treat osteoporosis, hypercalcaemia of malignancy, bone metastases, and Paget's disease in Singapore. Available as an intravenous infusion of 4mg–5mg administered annually for osteoporosis or every three to four weeks for oncology indications under clinical supervision, it is HSA-registered and available on prescription only in Singapore. Adequate hydration before infusion and dental assessment before initiation are mandatory as zoledronic acid carries a risk of acute phase reactions and osteonecrosis of the jaw in cancer patients on high-frequency dosing. A valid doctor's consultation is required before dispensing. Order Zoledronic Acid online at DoctorOnCall Singapore with same-day delivery available. Speak to a DoctorOnCall physician today to check if Zoledronic Acid is right for you.

Zoledronic Acid is a medication commonly used to treat and prevent bone-related conditions such as osteoporosis, Paget’s disease of bone, and bone complications caused by cancer (such as bone metastases and hypercalcaemia of malignancy). It works by inhibiting osteoclast activity, the cells responsible for bone breakdown, thereby strengthening bone density and reducing fracture risk. Zoledronic Acid belongs to a class of medications known as bisphosphonates and is widely used in bone and oncology care. Find affordable Zoledronic Acid options from trusted brands at DoctorOnCall.

Conclusion

Consult our doctors online for safe and effective use of Zoledronic Acid tailored to your health needs. Find the best prices for affordable Zoledronic Acid intravenous infusion formulations at DoctorOnCall Singapore.

Warnings

Kidney Use With Care

No dose adjustment needed in patients with a creatinine clearance of more than 35ml/min. However, Zoledronic Acid usage is not advisable in patients with a creatinine clearance of less than 35ml/min.

Alcohol Not Advisable

Although there is no known interaction between Zoledronic Acid and alcohol, excessive alcohol intake can cause bone loss which opposes the therapeutic uses of Zoledronic Acid.

Pregnancy Not Safe

Zoledronic Acid usage is not advisable during pregnancy as animal studies have shown toxic effects on the foetus. However, the potential risk for pregnant women is not known.

Driving Not advisable

Do not drive unless you are feeling well. Zoledronic Acid may cause side effects such as dizziness which could affect the ability to concentrate and drive.

Liver Use With Care

Zoledronic Acid is safe to use in patients with liver impairment.

Lactation Not Advisable

Zoledronic Acid usage is not advisable during breastfeeding as the excretion of Zoledronic Acid in human milk is unknown.

Frequently Asked Questions

Written by

Dr. Adeline Carol Peters, Bachelor of Medicine and Bachelor of Surgery (MBBS) — Manipal Academy of Higher Education (MAHE)

Reviewed by

Dr. Mohd Izzat Amir Bin Awang, Doctor of Medicine (MD), University of Mansoura - Manchester